ATRACTYLINE(DISCONTINUED)(SH)
- Product Name
- ATRACTYLINE(DISCONTINUED)(SH)
- CAS No.
- 6989-21-5
- Chemical Name
- ATRACTYLINE(DISCONTINUED)(SH)
- Synonyms
- Atractyline;(4aS,8aR)-3,8a-diMethyl-5-Methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan;ATRACTYLINE(DISCONTINUED)(SH);(4aS)-4,4aα,5,6,7,8,8a,9-Octahydro-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan;(4aS,8aR)-4,4a,5,6,7,8,8a,9-Octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan;Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-diMethyl-5-Methylene-, (4aS,8aR)-
- CBNumber
- CB6500946
- Molecular Formula
- C15H20O
- Formula Weight
- 216.32
- MOL File
- 6989-21-5.mol
ATRACTYLINE(DISCONTINUED)(SH) Property
- Melting point:
- 61-63℃
- Boiling point:
- 287.1±19.0℃ (760 Torr)
- Density
- 1.02±0.1 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 121.7±8.3℃
- storage temp.
- 2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Soild
- color
- Faint red to very dark red
- InChI
- InChI=1S/C15H20O/c1-10-5-4-6-15(3)8-14-12(7-13(10)15)11(2)9-16-14/h9,13H,1,4-8H2,2-3H3/t13-,15+/m0/s1
- InChIKey
- TYPSVDGIQAOBAD-DZGCQCFKSA-N
- SMILES
- O1C=C(C)C2C[C@]3([H])[C@@](C)(CC1=2)CCCC3=C
- LogP
- 5.570
N-Bromosuccinimide Price
- Product number
- SML3510
- Product name
- Atractylon
- Purity
- ≥85% (HPLC)
- Packaging
- 5MG
- Price
- $87.2
- Updated
- 2023/06/20
- Product number
- SML3510
- Product name
- Atractylon
- Purity
- ≥85% (HPLC)
- Packaging
- 25MG
- Price
- $351
- Updated
- 2023/06/20
- Product number
- FA74011
- Product name
- Atractylon
- Packaging
- 2mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA74011
- Product name
- Atractylon
- Packaging
- 25mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- FA74011
- Product name
- Atractylon
- Packaging
- 5mg
- Price
- $100
- Updated
- 2021/12/16
ATRACTYLINE(DISCONTINUED)(SH) Chemical Properties,Usage,Production
Chemical Properties
Yellow liquid, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Atractylodes macrocephala and Atractylodes lancea.
Uses
Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].
Definition
ChEBI: Atractylone is a sesquiterpenoid.
Biological Activity
Atractylon is a main active component of Atractylodis Rhizoma th at exhibits antibacterial, antiviral, anti-inflammatory, anti-allergic, anticancer, gastroprotective and neuroprotective activities. Atractylon inhibits proliferation, induces apoptosis and blocks invasion in varies hepatic cancer cell lines. It inhibits the expression of Bcl-2 and promotes the expression of Bax.
target
IL Receptor | VEGFR | Histamine Receptor
References
[1] Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10. DOI:10.3892/mmr.2016.5713
[2] Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68. DOI:10.1016/j.cbi.2016.08.015
ATRACTYLINE(DISCONTINUED)(SH) Preparation Products And Raw materials
Raw materials
Preparation Products
ATRACTYLINE(DISCONTINUED)(SH) Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@apinchemicals.com
- Country
- United Kingdom
- ProdList
- 6184
- Advantage
- 60
View Lastest Price from ATRACTYLINE(DISCONTINUED)(SH) manufacturers
- Product
- Atractylon 6989-21-5
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-26
- Product
- ATRACTYLINE(DISCONTINUED)(SH) 6989-21-5
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09