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OSELTAMIVIR ACID

Product Name
OSELTAMIVIR ACID
CAS No.
187227-45-8
Chemical Name
OSELTAMIVIR ACID
Synonyms
Oseltamivir carboxylate;Oseltamivir impurity C;(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid;Gs4071;Gs 4071;Gs-4071;Aids095377;Aids-095377;Oseltamiviracid/GS4071;Oseltamivir acid, >=98%
CBNumber
CB6501589
Molecular Formula
C14H24N2O4
Formula Weight
284.35
MOL File
187227-45-8.mol
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OSELTAMIVIR ACID Property

Melting point:
183-185°C
Boiling point:
508.7±50.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
≥14.2 mg/mL in DMSO; ≥46.1 mg/mL in H2O with gentle warming; ≥97 mg/mL in EtOH with gentle warming
pka
4.13±0.60(Predicted)
form 
Solid
color 
White to off-white
EPA Substance Registry System
1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- (187227-45-8)
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Safety

HS Code 
9999999999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001340
Product name
Oseltamivir impurity C
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001340
Price
$220
Updated
2024/03/01
Cayman Chemical
Product number
15779
Product name
Oseltamivir Acid
Purity
≥95%
Packaging
500μg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
15779
Product name
Oseltamivir Acid
Purity
≥95%
Packaging
1mg
Price
$82
Updated
2024/03/01
Cayman Chemical
Product number
15779
Product name
Oseltamivir Acid
Purity
≥95%
Packaging
5mg
Price
$380
Updated
2024/03/01
Cayman Chemical
Product number
15779
Product name
Oseltamivir Acid
Purity
≥95%
Packaging
10mg
Price
$711
Updated
2024/03/01
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OSELTAMIVIR ACID Chemical Properties,Usage,Production

Description

Oseltamivir (GS-4104) is an antiviral prodrug targeted against the influenza viruses. Oseltamivir acid is the active metabolite of oseltamivir. It acts as an inhibitor of influenza neuraminidases A and B (IC50 = 0.1 to 4.9 nM for both enzymes), in this way preventing virus budding and release.

Chemical Properties

White Solid

Uses

Oseltamivir Acid (Oseltamivir EP Impurity C) is a metabolite of Oseltamivir (O701000). It is a COVID19-related research product.

Uses

Oseltamivir Acid is a metabolite of Oseltamivir (O701000).

Definition

ChEBI: A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). A antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza.

References

[1] enguang feng, deju ye, jian li, dengyou zhang, jinfang wang, fei zhao, rolf hilgenfeld, mingyue zheng, hualiang jiang and hong liu. recent advances in neuraminidase inhibitor development as anti-influenza drugs. chem med chem 2012, 7: 1527 – 1536.
[2] tom jefferson reviewer, mark jones, peter doshi, elizabeth a spencer, igho onakpoya, carl j heneghan. oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comment. bmj. 2014, 348: g2545.
[3] rashmi dixit, gulam khandaker, scott ilgoutz, harunor rashid and robert booy. emergence of oseltamivir resistance: control and management of influenza before, during and after the pandemic. infectious disorders – drug targets. 2013, 13 (1): 34-45.

OSELTAMIVIR ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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OSELTAMIVIR ACID Suppliers

Musechem
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+1-800-259-7612
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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InvivoChem
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+1-708-310-1919 +1-13798911105
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708-557-7486
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sales@invivochem.cn
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United States
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Standardpharm Co. Ltd.
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86-714-3992388
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United States
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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United States
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Cayman Chemical Company
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View Lastest Price from OSELTAMIVIR ACID manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Oseltamivir EP Impurity C 187227-45-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-13
Guangzhou PI PI BIOTECH INC
Product
Oseltamivir Impurity C (EP) 187227-45-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-05-31
Hangzhou Huarong Pharm Co., Ltd.
Product
(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid 187227-45-8
Price
US $0.00/mg
Min. Order
10mg
Purity
99%
Supply Ability
10KG
Release date
2021-09-14

187227-45-8, OSELTAMIVIR ACIDRelated Search:


  • (3R,4R,5S)-4-acetamido-5-amino-3
  • Oseltamivir Phosphate Impurity Ⅲ
  • (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylic Acid
  • Oseltamivir Impurity C (EP)
  • Oseltamivir Carboxylic Acid HCl
  • GS 4071;RO 64-0802;OSELTAMIVIR CARBOXYLATE
  • (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
  • (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohex-ene-1-carboxylic acid
  • 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)-
  • 204255-11-8 (Monophospate salt)
  • Aids095377
  • Aids-095377
  • Gs 4071
  • Gs4071
  • Gs-4071
  • Oseltamivir carboxylate
  • OseltamivirCarboxylicAcid,4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylicAcid
  • OseltaMivir carboxylic acid
  • (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylic acid
  • Oseltamivir impurity C
  • Oseltamivir carboxylate (OC)
  • Oseltamivir acid, >=98%
  • Oseltamivir EP Impurity C
  • Oseltamivir carboxylate (OC),Metabolite of oseltamivir
  • (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid
  • Oseltamivir Phosphate impurity C (EP)
  • Oseltamivir Impurity 3 Monomer(Oseltamivir EP Impurity C Monomer)
  • Oseltamivir acid formate salt
  • Oseltamivir EP Impurity C (Oseltamivir Acid)
  • Oseltamivir carboxylate (GS 4071
  • Oseltamivir Impurity476
  • Oseltamivir carboxylic acidQ: What is Oseltamivir carboxylic acid Q: What is the CAS Number of Oseltamivir carboxylic acid Q: What is the storage condition of Oseltamivir carboxylic acid
  • Oseltamivir impurity C (Y0001340)Q: What is Oseltamivir impurity C (Y0001340) Q: What is the CAS Number of Oseltamivir impurity C (Y0001340)
  • Drug Metabolite,Inhibitor,Influenza Virus,Oseltamivir acid,GS4071,GS-4071,inhibit
  • Oseltamiviracid/GS4071
  • Oseltamivir Phosphate Impurity C
  • Oseltamivir Acid Impurity
  • 187227-45-8
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