ChemicalBook > CAS DataBase List > UAMC-3203 hydrochloride

UAMC-3203 hydrochloride

Product Name: UAMC-3203 hydrochloride
CAS No.: 2271358-65-5
Chemical Name: UAMC-3203 hydrochloride
Synonyms: UAMC-3203HCl;UAMC-3203 hydrochloride;UAMC-3203 hydrochloride, 10 mM in DMSO;UAMC 3203 hydrochloride,UAMC3203,UAMC 3203,inhibit,UAMC-3203,Inhibitor,Ferroptosis,UAMC3203 hydrochloride;4-(cyclohexylamino)-3-[(phenylmethyl)amino]-N-[2-(1-piperazinyl)ethyl]-benzenesulfonamide, monohydrochloride
CBNumber: CB65419867
Molecular Formula: C25H38ClN5O2S
Formula Weight: 508.12
MOL File: 2271358-65-5.mol

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UAMC-3203 hydrochloride Property

storage temp.: 4°C, away from moisture and light
solubility: DMF: 10mg/mL; DMSO: 25mg/mL; DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29346
Product name: UAMC-3203 (hydrochloride)
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 29346
Product name: UAMC-3203 (hydrochloride)
Packaging: 25mg
Price: $305
Updated: 2024/03/01

Cayman Chemical

Product number: 29346
Product name: UAMC-3203 (hydrochloride)
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 29346
Product name: UAMC-3203 (hydrochloride)
Packaging: 10mg
Price: $153
Updated: 2024/03/01

AK Scientific

Product number: 2157EN
Product name: UAMC-3203hydrochloride
Packaging: 10mg
Price: $302
Updated: 2021/12/16

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UAMC-3203 hydrochloride Chemical Properties,Usage,Production

Uses

UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM[1].

in vivo

No toxicity is observed in mice after repeated injections of UAMC-3203 (20 μmol/kg; injected intraperitoneally; daily, over a period of 4 weeks)^[1].

Animal Model:	Wild type mice derived from a Gpx4 fl/fl breeding^[1]
Dosage:	20 μmol/kg
Administration:	Injected intraperitoneally; daily, over a period of 4 weeks
Result:	No toxicity was observed.

References

[1] Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140. DOI:10.1021/acs.jmedchem.8b01299

UAMC-3203 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2271358-65-5, UAMC-3203 hydrochlorideRelated Search:

UCPH-101

UAMC-3203 hydrochloride

UAMC-3203HCl

UAMC 3203 hydrochloride,UAMC3203,UAMC 3203,inhibit,UAMC-3203,Inhibitor,Ferroptosis,UAMC3203 hydrochloride

4-(cyclohexylamino)-3-[(phenylmethyl)amino]-N-[2-(1-piperazinyl)ethyl]-benzenesulfonamide, monohydrochloride

UAMC-3203 hydrochloride, 10 mM in DMSO

2271358-65-5