ChemicalBook > CAS DataBase List > Z433927330
Z433927330
- Product Name
- Z433927330
- CAS No.
- 1005883-72-6
- Chemical Name
- Z433927330
- Synonyms
- Z433927330;Z433927330, 10 mM in DMSO;Z 433927330,Z-433927330,inhibit,Inhibitor,Z433927330;Ethyl 4-(3-(4-(1H-pyrazol-1-yl)benzyl)ureido)benzoate;Benzoic acid, 4-[[[[[4-(1H-pyrazol-1-yl)phenyl]methyl]amino]carbonyl]amino]-, ethyl ester
- CBNumber
- CB65419872
- Molecular Formula
- C20H20N4O3
- Formula Weight
- 364.4
- MOL File
- 1005883-72-6.mol
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Z433927330 Property
- Boiling point:
- 532.4±50.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- pka
- 13.00±0.46(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC22267
- Product name
- Z433927330
- Purity
- >98%
- Packaging
- 100mg
- Price
- $750
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC22267
- Product name
- Z433927330
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1400
- Updated
- 2021/12/16
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Z433927330 Chemical Properties,Usage,Production
Uses
Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 μM, ~0.7 μM and ~1.1 μM for mAQP7, mAQP3 and mAQP9, respectively[1].
References
[1] Z433927330, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387. DOI:10.1074/jbc.RA118.006083
Z433927330 Preparation Products And Raw materials
Raw materials
Preparation Products
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