ChemicalBook > CAS DataBase List > 2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃

2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃

Product Name
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃
CAS No.
152065-54-8
Chemical Name
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃
Synonyms
Br-PEG2-THP;2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran;2H-Pyran, 2-[2-(2-bromoethoxy)ethoxy]tetrahydro-
CBNumber
CB65574591
Molecular Formula
C9H17BrO3
Formula Weight
253.13
MOL File
152065-54-8.mol
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2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 Property

Boiling point:
314.3±37.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
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Hazard and Precautionary Statements (GHS)

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2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 Chemical Properties,Usage,Production

Biological Activity

Bromo-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 Suppliers

Borenpharm Co., Ltd
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Wuhan Borenpharm Co., Ltd
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View Lastest Price from 2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran 2-[2-(2-溴乙氧基)乙氧基]四氢-2H-吡喃 manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Br-PEG2-THP 152065-54-8
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-25