KRT17 antibody
Applications Immunogen Background- Product Name
- KRT17 antibody
- Chemical Name
- KRT17 antibody
- Synonyms
- KRT17 antibody;Rabbit Polyclonal KRT17 Antibody
- CBNumber
- CB65650228
- Formula Weight
- 0
- MOL File
- Mol file
KRT17 antibody Chemical Properties,Usage,Production
Applications
KRT17 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Recommended starting dilution is 1:1000.
Immunogen
Anti-human KRT17 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KRT17 protein 1-432 amino acids purified from E. coli.
Background
Cytokeratin 17 also known as KRT17 is a type I cytokeratin. KRT17 is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. KRT17 takes part in the formation and maintenance of a variety of skin appendages, particularly in determining shape and orientation of hair. KRT17 also modulates the function of TNF-alpha in the precise context of hair cycling. Moreover, KRT17 regulates protein synthesis and epithelial cell growth all through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway.
KRT17 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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