NGF antibody
Source Reactivity Background References- Product Name
- NGF antibody
- Chemical Name
- NGF antibody
- Synonyms
- NGF antibody;Rabbit Polyclonal NGF Antibody
- CBNumber
- CB65666632
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb162009
- Product name
- NGF antibody
- Purity
- Affinity-purified by affinity-chromatography using epitope-specific immunogen.
- Packaging
- 100μg
- Price
- $280.5
- Updated
- 2021/12/16
- Product number
- orb379540
- Product name
- NGF antibody
- Purity
- ProA affinity purified
- Packaging
- 100μL
- Price
- $399.5
- Updated
- 2021/12/16
- Product number
- orb99174
- Product name
- NGF antibody
- Purity
- Immunogen affinity purified.
- Packaging
- 100μg
- Price
- $523.6
- Updated
- 2021/12/16
- Product number
- orb67212
- Product name
- NGF antibody
- Purity
- Affinity purification
- Packaging
- 100μL
- Price
- $656.2
- Updated
- 2021/12/16
NGF antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
Nerve growth factor is a small, secreted protein and member of the neurotrophin family of growth factors that promote neuronal cell survival and differentiation. Producing cells release NGF that bind and activate TrkA high affinity receptors to mediate NGF-driven signaling. NGF also binds to low affinity p75 receptors, which belong to the death receptor family. Although NGF has been classically described as favoring neuron survival and differentiation, NGF can promote apoptosis in cells that contain p75 and lack TrkA. NGF can induce neuron death in a variety of neurodegenerative conditions, including Alzheimer's disease. Besides its neurotrophic actions, NGF has an effect on non-neuronal cells and may help mediate inflammation, angiogenesis, and stimulate breast cancer cell growth. NGF signaling is looking increasingly promising as potential drug targets for diseases.
References
[1] Lessmann, V. et al. (2003) Prog Neurobiol 69, 341-74.
[2] Neet, K.E. and Campenot, R.B. (2001) Cell Mol Life Sci 58, 1021-35.
[3] Lorigados-Pedre, L. and Bergado-Rosado, J. (2004) Rev Neurol 38, 957-71.
[4] Frossard, N. et al. (2004) Eur J Pharmacol 500, 453-65.
[5] Nico, B. et al. (2008) Microvasc Res 75, 135-41.
[6] Descamps, S. et al. (2001) J Biol Chem 276, 17864-70.
NGF antibody Preparation Products And Raw materials
Raw materials
Preparation Products
NGF antibody Suppliers
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