ROR1 antibody
Source Reactivity Background References- Product Name
- ROR1 antibody
- Chemical Name
- ROR1 antibody
- Synonyms
- ROR1 antibody
- CBNumber
- CB65693115
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb608121
- Product name
- ROR1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb608121
- Product name
- ROR1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
ROR1 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse
Background
ROR1 and ROR2 are orphan receptor tyrosine kinases that are most closely related to MuSK and the Trk family of neurotrophin receptors. They are characterized by the presence of extracellular frizzled-like cysteine-rich domains and membrane-proximal kringle domains, both of which are assumed to mediate protein-protein interactions. The ROR family RTKs are evolutionarily conserved among Caenorhabditis elegans, Drosophila, mice, and humans. Although the functions of ROR kinases are unknown, similarities between ROR and MuSK and Trk kinases have led to speculation that ROR kinases regulate synaptic development. CAM-1, a C. elegans ortholog of the ROR family RTKs, plays several important roles in regulating cellular migration, polarity of asymmetric cell divisions, and axonal outgrowth of neurons during nematode development. mROR1 and mROR2 may play differential roles during the development of the nervous system.
References
[1] Al-Shawi, R. et al. (2001) Dev Genes Evol 211, 161-71.
[2] Nomi, M. et al. (2001) Mol Cell Biol 21, 8329-35.
[3] Roszmusz, E. et al. (2001) J Biol Chem 276, 18485-90.
[4] Forrester, W.C. et al. (1999) Nature 400, 881-5.
[5] Oishi, I. et al. (1999) Genes Cells 4, 41-56.
ROR1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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