Applications Immunogen Background

TXN2 antibody

Applications Immunogen Background
Product Name
TXN2 antibody
Chemical Name
TXN2 antibody
Synonyms
TXN2 antibody;Rabbit Polyclonal TXN2 Antibody
CBNumber
CB65703122
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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TXN2 antibody Chemical Properties,Usage,Production

Applications

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity.

Immunogen

Anti-human TXN2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TXN2 protein 60-166 amino acids purified from E. coli.

Background

Thioredoxin-2 is a low molecular weight redox protein. TRX2 contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The TXN2 is involved in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Upon stimulation of Fas, TXN2 mediates denitrosylation of mitochondria-associated caspase-3, a process required for caspase-3 activation, and promoted apoptosis.
TRX2 is important at low oxidative stress conditions.
MTRX is involved in the regulation of the mitochondrial membrane potential and cell death. Mitochondrial thioredoxin plays an important roles in protection against oxidant-induced apoptosis. Thioredoxin1 and thioredoxin2 have opposed regulatory functions on hypoxia-inducible factor-1alpha.

TXN2 antibody Preparation Products And Raw materials

Raw materials

Preparation Products

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TXN2 antibody Suppliers

CHINA 43 Global 43
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  • TXN2 antibody
  • Rabbit Polyclonal TXN2 Antibody