ChemicalBook > CAS DataBase List > tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

Product Name
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
CAS No.
2375541-45-8
Chemical Name
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Synonyms
187407;Autogramin-2;Autogramin-2, 10 mM in DMSO;Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2;tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester
CBNumber
CB65708228
Molecular Formula
C21H27N3O4S
Formula Weight
417.52
MOL File
2375541-45-8.mol
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tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Property

Density 
1.252±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO (up t0 25 mg/ml) or in Ethanol (up to 25 mg/ml)
form 
solid
pka
7.59±0.20(Predicted)
color 
Off-white
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BA171490
Product name
Autogramin 2
Packaging
5mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
BA171490
Product name
Autogramin 2
Packaging
10mg
Price
$135
Updated
2021/12/16
Biosynth Carbosynth
Product number
BA171490
Product name
Autogramin 2
Packaging
25mg
Price
$287.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
BA171490
Product name
Autogramin 2
Packaging
50mg
Price
$472.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
BA171490
Product name
Autogramin 2
Packaging
100mg
Price
$700
Updated
2021/12/16
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tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Chemical Properties,Usage,Production

Description

Autogramin-2 (2375541-45-8) is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A).? Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.

References

References/Citations:

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Suppliers

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2375541-45-8, tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylateRelated Search:

3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide Dequalinium chloride NORFLUOXETINE HYDROCHLORIDE DO264 TERT-BUTYL 2-(6-CHLOROPYRIDIN-3-YL)ETHYLCARBAMATE

  • tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
  • 187407
  • Autogramin-2
  • Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester
  • Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2
  • Autogramin-2, 10 mM in DMSO
  • 2375541-45-8