Homo-PROTAC cereblon degrader 1

Product Name: Homo-PROTAC cereblon degrader 1
CAS No.: 2244520-98-5
Chemical Name: Homo-PROTAC cereblon degrader 1
Synonyms: Homo-PROTAC cereblon degrader 1;Homo-PROTAC cereblon degrader 1 ，S2881;Homo-PROTAC cereblon degrader 1,PROTACs,Inhibitor,inhibit,HomoPROTAC cereblon degrader 1,Homo PROTAC cereblon degrader 1;4,4'-(((Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(azanediyl))bis(2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione);2-(2,6-dioxopiperidin-3-yl)-4-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethyl}amino)-2,3-dihydro-1H-isoindole-1,3-dione
CBNumber: CB65848830
Molecular Formula: C32H32N6O10
Formula Weight: 660.64
MOL File: 2244520-98-5.mol

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Homo-PROTAC cereblon degrader 1 Property

Boiling point:: 978.5±65.0 °C(Predicted)
Density: 1.527±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 200 mg/mL (302.74 mM)
pka: 10.44±0.40(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm

Product number: CSN23924
Product name: Homo-PROTACcereblondegrader1
Packaging: 1mg
Price: $60
Updated: 2021/12/16

CSNpharm

Product number: CSN23924
Product name: Homo-PROTACcereblondegrader1
Packaging: 5mg
Price: $100
Updated: 2021/12/16

CSNpharm

Product number: CSN23924
Product name: Homo-PROTACcereblondegrader1
Packaging: 10mg
Price: $170
Updated: 2021/12/16

CSNpharm

Product number: CSN23924
Product name: Homo-PROTACcereblondegrader1
Packaging: 25mg
Price: $280
Updated: 2021/12/16

DC Chemicals

Product number: 025868
Product name: Homo-PROTACcereblondegrader1
Packaging: 001
Price: $750
Updated: 2021/12/16

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Homo-PROTAC cereblon degrader 1 Chemical Properties,Usage,Production

Description

Homo-PROTAC Cereblon Degrader 1 is a highly potent and efficient Cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.

Uses

Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient Cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3[1].

IC 50

Cereblon

References

[1] Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782. DOI:10.1021/acschembio.8b00693

Homo-PROTAC cereblon degrader 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Homo-PROTAC cereblon degrader 1 Suppliers

China 37 United States 5 Global 42

Shanghai EFE Biological Technology Co., Ltd.

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2244520-98-5, Homo-PROTAC cereblon degrader 1Related Search:

Homo-PROTAC pVHL30 degrader 1 Halo PROTAC 1

Homo-PROTAC cereblon degrader 1

4,4'-(((Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(azanediyl))bis(2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione)

Homo-PROTAC cereblon degrader 1,PROTACs,Inhibitor,inhibit,HomoPROTAC cereblon degrader 1,Homo PROTAC cereblon degrader 1

2-(2,6-dioxopiperidin-3-yl)-4-({2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethyl}amino)-2,3-dihydro-1H-isoindole-1,3-dione

Homo-PROTAC cereblon degrader 1 ，S2881

2244520-98-5

C32H32N6O10