Boc-Val-Ala-PAB-PNP

Uses In vitro Storage

Product Name: Boc-Val-Ala-PAB-PNP
CAS No.: 1884578-00-0
Chemical Name: Boc-Val-Ala-PAB-PNP
Synonyms: Boc-Val-Ala-PAB-PNP;Boc-Val-Ala-PAB-PNP USP/EP/BP;6-Maleimidohexanoyl-valyl-alanyl-(4-aminobenzyl)-(4-nitrophenyl)-carbonate;4-[(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]propanamido]benzyl (4-Nitrophenyl) Carbonate;L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;tert-Butyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)carbamate
CBNumber: CB65864429
Molecular Formula: C27H34N4O9
Formula Weight: 558.58
MOL File: 1884578-00-0.mol

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Boc-Val-Ala-PAB-PNP Property

Boiling point:: 793.1±60.0 °C(Predicted)
Density: 1.269±0.06 g/cm3(Predicted)
form: Solid
pka: 11.26±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Iris Biotech GmbH

Product number: ADC1050
Product name: Boc-Val-Ala-PAB-PNP
Packaging: 100mg
Price: $168.75
Updated: 2021/12/16

Iris Biotech GmbH

Product number: ADC1050
Product name: Boc-Val-Ala-PAB-PNP
Packaging: 250mg
Price: $337.5
Updated: 2021/12/16

Iris Biotech GmbH

Product number: ADC1050
Product name: Boc-Val-Ala-PAB-PNP
Packaging: 1g
Price: $1012.5
Updated: 2021/12/16

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Boc-Val-Ala-PAB-PNP Chemical Properties,Usage,Production

Uses

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

In vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Description

Boc-Val-Ala-PAB-PNP can be used to design cleavable ADC linkers. The Val-Ala, as shown in the ACD Zynlonta, is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Boc-Val-Ala-PAB-PNP Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-Val-Ala-PAB-PNP Suppliers

China 44 United States 3 Global 47

Heze Development Zone chuangli Chemical Co., Ltd.

Tel: +86-530-529 6766，+86-15666160102 15666160102
Fax: 0530-529 6766
Email: info@chuangli-chem.com
Country: China
ProdList: 897
Advantage: 55

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 878
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11578
Advantage: 59

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q3252066219
Fax: QQ3382968513
Email: danping@shsendpharm.com
Country: China
ProdList: 3096
Advantage: 55

ATK CHEMICAL COMPANY LIMITED

Tel: 021-51619050 13301662590
Fax: +86-21-51619052
Email: mandy@atkchemical.com
Country: China
ProdList: 10199
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7298
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Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4825
Advantage: 58

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View Lastest Price from Boc-Val-Ala-PAB-PNP manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Boc-Val-Ala-PAB-PNP 1884578-00-0
Price: US $0.00/g
Min. Order: 1g
Purity: >95.00%
Supply Ability: 1g
Release date: 2024-03-29

1884578-00-0, Boc-Val-Ala-PAB-PNPRelated Search:

Boc-Val-Ala-PAB-PNP

L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

Boc-Val-Ala-PAB-PNP USP/EP/BP

4-[(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]propanamido]benzyl (4-Nitrophenyl) Carbonate

tert-Butyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)carbamate

6-Maleimidohexanoyl-valyl-alanyl-(4-aminobenzyl)-(4-nitrophenyl)-carbonate

1884578-00-0

ADC LINKER

Linker