TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE

Product Name: TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE
CAS No.: 864771-44-8
Chemical Name: TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE
Synonyms: 2-(1-Bo;1-Boc-indazole-5-boronic acid pinacol ester;1-Boc-indazolyl-5-boronic Acid Pinacol Ester;1-Boc-1H-indalzole-5-boronic acid picol ester;1-Boc-1H-indalzole-5-boronic acid pinacol ester;1H-Indazole-5-boronic acid pinacol ester, N1-BOC protected;1-(tert-Butoxycarbonyl)indazolyl-5-boronic Acid Pinacol Ester;1-Boc-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole;1-(tert-Butoxycarbonyl)-1H-indazole-5-boronic acid pinacol ester;1-Boc-5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CBNumber: CB6589574
Molecular Formula: C18H25BN2O4
Formula Weight: 344.21
MOL File: 864771-44-8.mol

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TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE Property

Melting point:: 110 °C
Boiling point:: 461.4±37.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.48±0.30(Predicted)
form: solid
Appearance: White to off-white Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 22-26-36/37/39
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CVT00055
Product name: 1-Boc-5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole, contains isomer
Packaging: 1g
Price: $356
Updated: 2025/07/31

TCI Chemical

Product number: B5992
Product name: 1-(tert-Butoxycarbonyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole
Purity: min. 98.0 %
Packaging: 200MG
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: B5992
Product name: 1-(tert-Butoxycarbonyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole
Purity: min. 98.0 %
Packaging: 1G
Price: $159
Updated: 2025/07/31

TRC

Product number: B682943
Product name: 1-Boc-indazole-5-boronicacid,pinacolester
Packaging: 50mg
Price: $55
Updated: 2021/12/16

Usbiological

Product number: 409023
Product name: 1-Boc-indazole-5-boronic acid, pinacol ester
Packaging: 25mg
Price: $305
Updated: 2021/12/16

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TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

651780-02-8

73183-34-3

864771-44-8

Tert-butyl 5-bromo-1H-indazole-1-carboxylate (10.1 mmol) and pinacol ester of bisboronic acid (11.1 mmol) were used as raw materials for the reaction catalyzed by palladium(II) acetate (1.01 mmol) and dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) (1.01 mmol) with the addition of potassium acetate (30.3 mmol) in triethylamine ( 1.5 mL) solution of potassium acetate (30.3 mmol) and 1,4-dioxane (60 mL) as a solvent, and the reaction was carried out at 110 °C overnight. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was purified by fast column chromatography (eluent: 5% ethyl acetate/petroleum ether) to afford the target product 1-tert-butoxycarbonylindazole-5-boronic acid pinacol ester as a yellow solid in 74% yield.

References

[1] Patent: WO2011/66211, 2011, A1. Location in patent: Page/Page column 69-70
[2] Organic Letters, 2009, vol. 11, # 13, p. 2860 - 2863
[3] Patent: WO2010/59943, 2010, A2. Location in patent: Page/Page column 83; 84
[4] Patent: WO2006/86705, 2006, A1. Location in patent: Page/Page column 89
[5] Patent: US2008/153813, 2008, A1. Location in patent: Page/Page column 22

TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE Suppliers

Americas 1 China 63 Europe 1 France 1 Germany 1 India 2 Japan 1 United Kingdom 3 United States 18 Global 91

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

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View Lastest Price from TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE manufacturers

Career Henan Chemical Co

Product: TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE 864771-44-8
Price: US $6.60/KG
Min. Order: 500g
Purity: 98%
Supply Ability: 1KG, 50KG, 100KG
Release date: 2019-12-25

864771-44-8, TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATERelated Search:

TERT-BUTYL FORMATE INDAZOLE-5-BORONIC ACID PINACOL ESTER 1H-INDAZOLE-5-BORONIC ACID 1-METHYLINDAZOL-5-BORONIC ACID TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE-1-CARBOXYLATE

1-(tert-Butoxycarbonyl)-1H-indazole-5-boronic acid pinacol ester

1-Boc-indazole-5-boronic acid pinacol ester

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate

5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)- indazole-1-carboxylic acid tert-butyl ester

tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate, 1-(tert-Butoxycarbonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

1H-Indazole-1-carboxylicacid,5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-,1,1-diMethylethylester

tert-butyl 5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate

1-Boc-5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

1-Boc-1H-indalzole-5-boronic acid pinacol ester

1-Boc-5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole, contains isomer

tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate

tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-indole-1-carboxyla

1H-Indazole-5-boronic acid pinacol ester, N1-BOC protected

1-Boc-1H-indalzole-5-boronic acid picol ester

1-(tert-Butoxycarbonyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole

1-(tert-Butoxycarbonyl)indazolyl-5-boronic Acid Pinacol Ester

1-Boc-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)indazole

1-Boc-indazolyl-5-boronic Acid Pinacol Ester

2-(1-Bo

2-(1-tert-Butoxycarbonyl-5-indazolyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole-1-carboxylate

tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazol-1-carboxylate

tert-butyl 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)indazole-1-carboxylate

tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate - [B13702]

864771-44-8

C18H25BN2O4

Indazoles