ChemicalBook > CAS DataBase List > A-3 HYDROCHLORIDE

A-3 HYDROCHLORIDE

Product Name
A-3 HYDROCHLORIDE
CAS No.
78957-85-4
Chemical Name
A-3 HYDROCHLORIDE
Synonyms
A-3;A-3 HYDROCHLORIDE;TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE;1-Naphthalenesulfonamide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1);Calmodulin-dependent kinases,CaMK,inhibit,Casein Kinase,PKC,inhibitor,PKA,A 3 hydrochloride,cAMP,calmodulin,kinase,A-3,MLC-kinase,Calmodulin-dependent protein kinases,Protein kinase C,Protein kinase A,A 3,casein,A3 hydrochloride
CBNumber
CB6664789
Molecular Formula
C12H14Cl2N2O2S
Formula Weight
321.22
MOL File
78957-85-4.mol
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A-3 HYDROCHLORIDE Property

Melting point:
173-176°C
storage temp. 
-20°C
solubility 
DMSO: 24 mg/mL
form 
solid
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2935909099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A1980
Product name
A3 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$177
Updated
2024/03/01
Sigma-Aldrich
Product number
A1980
Product name
A3 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$550
Updated
2023/06/20
TRC
Product number
A608900
Product name
N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide,Hydrochloride
Packaging
250mg
Price
$1355
Updated
2021/12/16
TRC
Product number
A608900
Product name
N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide,Hydrochloride
Packaging
25mg
Price
$175
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
KIN0000018
Product name
A-3 HYDROCHLORIDE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
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A-3 HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C

Biochem/physiol Actions

Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM).

A-3 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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A-3 HYDROCHLORIDE Suppliers

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78957-85-4, A-3 HYDROCHLORIDERelated Search:

N-(2-aminoethyl)-4-methyl-benzenesulfonamide N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA N-(2-AMINOETHYL)METHANESULFONAMIDE N-(2-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE N-(2-Aminoethyl)-N-benzylglycine Bis(trifluoroacetate) N-(2-aminoethyl)-N-methylmethanesulfonamide hydrochloride 1-(2,4-DICHLOROPHENYL)HYDRAZINE HYDROCHLORIDE 1-(2,4-DIFLUOROPHENYL)HYDRAZINE HYDROCHLORIDE 1-(2,6-DICHLOROPHENYL)HYDRAZINE HYDROCHLORIDE 1-Chloronaphthalene 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE (+/-)-1-(2,5-DIMETHOXY-4-IODOPHENYL)-2-AMINOPROPANE HYDROCHLORIDE 1,2,5,6-TETRAHYDRO-1-METHYL-NICOTINIC ACID HYDROCHLORIDE [+/-]-1-[2,5-DIMETHOXYPHENYL]-2-GLYCINAMIDOETHANOL HYDROCHLORIDE 1-(2,4-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE 1-(2,3-DIMETHYLPHENYL)PIPERAZINE HYDROCHLORIDE 1-(2,5-DIMETHOXYBENZYL)PIPERAZINE HYDROCHLORIDE 10,11-dihydro-5-(3-(dimethylamino)propyl)-5h-dibenz[b,f]azepine hydrochloride

  • A-3 HYDROCHLORIDE
  • A-3
  • TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY
  • N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL
  • N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE
  • N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE
  • N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
  • 1-Naphthalenesulfonamide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1)
  • Calmodulin-dependent kinases,CaMK,inhibit,Casein Kinase,PKC,inhibitor,PKA,A 3 hydrochloride,cAMP,calmodulin,kinase,A-3,MLC-kinase,Calmodulin-dependent protein kinases,Protein kinase C,Protein kinase A,A 3,casein,A3 hydrochloride
  • 78957-85-4
  • C12H13ClN2O2SHCl
  • C12H13ClN2O2SClH
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Casein Kinase (CK)
  • Serine/Threonine Kinase Inhibitors
  • Kinase/Phosphatase Biology
  • Protein Kinase Inhibitors and Activators
  • Protein Kinase