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2'-FLUORO AEA

Product Name
2'-FLUORO AEA
CAS No.
166100-37-4
Chemical Name
2'-FLUORO AEA
Synonyms
AFEA;2'-FLUORO AEA;AEA, 2'-FLUORO;-fluoroethylamide;Arachidonyl-2’2'-FLUORO ANANDAMIDE;Arachidonoyl-2’ANANDAMIDE, 2'-FLUORO;FLUOROETHYLEICOSATETRAENAMIDE;Arachidonyl-2-fluoroethylamide
CBNumber
CB6666556
Molecular Formula
C22H36FNO
Formula Weight
349.53
MOL File
166100-37-4.mol
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2'-FLUORO AEA Property

Boiling point:
496.0±45.0 °C(Predicted)
Density 
0.925±0.06 g/cm3(Predicted)
solubility 
DMF: 10 mg/ml; DMSO: 7 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (1:1): 8 mg/ml
pka
15.24±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
90054
Product name
Arachidonoyl-2'-Fluoroethylamide
Purity
≥98%
Packaging
5mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
90054
Product name
Arachidonoyl-2'-Fluoroethylamide
Purity
≥98%
Packaging
10mg
Price
$89
Updated
2024/03/01
Cayman Chemical
Product number
90054
Product name
Arachidonoyl-2'-Fluoroethylamide
Purity
≥98%
Packaging
50mg
Price
$371
Updated
2024/03/01
Cayman Chemical
Product number
90054
Product name
Arachidonoyl-2'-Fluoroethylamide
Purity
≥98%
Packaging
100mg
Price
$646
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
LIP0005000
Product name
2'-FLUORO AEA
Purity
95.00%
Packaging
5MG
Price
$503.79
Updated
2021/12/16
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2'-FLUORO AEA Chemical Properties,Usage,Production

Description

Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution adds considerably increased binding affinity for the CB1 receptor (Kis = 26.7 and 908 nM for CB1 and CB2, respectively). It also contributes additional selectivity, in that binding to CB2 is decreased relative to AEA.1 However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme.

Uses

Arachidonoyl-2'-fluoroethylamide is a CB1 receptor agonist and an analog of Anandamide (A637220), which is an endogenous cannabinoid and TRPV1 receptor agonist.

References

1. Lin, S., Khanolkar, A.D., Fan, P., et al. Novel analogues of arachidonylethanolamide (anandamide): Affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability J. Med. Chem. 41(27),5353-5361(1998).

2'-FLUORO AEA Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-FLUORO AEA Suppliers

China 7 Italy 1 Switzerland 2 United States 2 USA 1 Global 13
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
SHANGHAI ZZBIO CO., LTD.
Tel
15102117276 19921389125
Email
tech@zzbioco.com
Country
China
ProdList
12065
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

166100-37-4, 2'-FLUORO AEARelated Search:

ANANDAMIDE O-689 2'-FLUORO AEA

  • FLUOROETHYLEICOSATETRAENAMIDE
  • ARACHIDONOYL 2'-FLUOROETHYLAMIDE
  • AFEA
  • AEA, 2'-FLUORO
  • ANANDAMIDE, 2'-FLUORO
  • 2'-FLUORO AEA
  • 2'-FLUORO ANANDAMIDE
  • N-(2-FLUOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE
  • Arachidonyl-2-fluoroethylamide
  • Arachidonoyl-2&rsquo
  • 5,8,11,14-Eicosatetraenamide, N-(2-fluoroethyl)-, (5Z,8Z,11Z,14Z)-
  • Arachidonyl-2&rsquo
  • -fluoroethylamide
  • Arachidonoyl-2'-Fluoroethylamide
  • 166100-37-4