(S,S)-2,8-Diazabicyclo[4,3,0]nonane

Product Name: (S,S)-2,8-Diazabicyclo[4,3,0]nonane
CAS No.: 151213-42-2
Chemical Name: (S,S)-2,8-Diazabicyclo[4,3,0]nonane
Synonyms: (S,S)-2,8-Diazabicyclo Nonane;Moxifloxacin-23;Moxifloxacin Nonane;Moxifloxacin side chain;Moxifloxacin Impurity S2;Moxifloxacin (R,R)-Nonane;MOXIFLOXACIN INTERMEDIATES;Moxifloxacin Intermediate 1;(S,S)-2,8-Diazabicyclo[4,3,0];Azilsartan medoxomil impurity274
CBNumber: CB6666778
Molecular Formula: C7H14N2
Formula Weight: 126.2
MOL File: 151213-42-2.mol

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(S,S)-2,8-Diazabicyclo[4,3,0]nonane Property

Boiling point:: 198.5±8.0 °C(Predicted)
Density: 0.950±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Methanol (Slightly), Water
pka: 11.11±0.20(Predicted)
form: Oil
color: Colourless to Yellow
InChI: InChI=1S/C7H14N2/c1-2-6-4-8-5-7(6)9-3-1/h6-9H,1-5H2/t6-,7+/m1/s1
InChIKey: KSCPLKVBWDOSAI-RQJHMYQMSA-N
SMILES: [C@]12([H])CNC[C@@]1([H])CCCN2
CAS DataBase Reference: 151213-42-2(CAS DataBase Reference)

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Safety

HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D417275
Product name: (1R,6R)-2,8-Diazabicyclo[4.3.0]nonane(TechnicalGrade)
Packaging: 100mg
Price: $605
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: APN0000020
Product name: (S,S)-2,8-DIAZABICYCLO(4,3,0)NONANE
Purity: 95.00%
Packaging: 1G
Price: $496
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: APN0000020
Product name: (S,S)-2,8-DIAZABICYCLO(4,3,0)NONANE
Purity: 95.00%
Packaging: 2.5G
Price: $769.05
Updated: 2021/12/16

Chemcia Scientific

Product number: CC00-8110
Product name: (S,S)-Octahydro-pyrrolo[3,4-b]pyridine
Purity: 97%
Packaging: 25g
Price: $760
Updated: 2021/12/16

Ambeed

Product number: A372965
Product name: (4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine
Purity: 98%
Packaging: 5g
Price: $45
Updated: 2021/12/16

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(S,S)-2,8-Diazabicyclo[4,3,0]nonane Chemical Properties,Usage,Production

Chemical Properties

Clear light red liquid

Uses

(1R,6R)-2,8-Diazabicyclo[4.3.0]nonane is a chiral reagent used in the synthesis of pyrrolopyrimidine derivatives as dual DNA gyrase B and topoisomerase IV inhibitors and potential antibacterial agents.

Synthesis

151213-43-3

151213-42-2

The general procedure for the synthesis of (4aR,7aR)-octahydro-6-(phenylmethyl)-1H-pyrrolo[3,4-b]pyridine from (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine is as follows: 19.4 g (0.09 mol) of (R,R)-8-benzyl-2,8-diazabicyclo[4.3.0]nonane was dissolved in methanol with the addition of 3.96 g of 5% palladium/activated carbon catalyst and hydrogenated at 90 °C and 130 °C for 5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the catalyst was washed with methanol. The filtrate was concentrated under vacuum and the residue was directly distilled without fractionation. A final product of 9.61 g was obtained in 85% yield of the theoretical value. The boiling point of the product was 45-58°C/0.08 mbar.

References

[1] Patent: WO2003/106450, 2003, A1. Location in patent: Page column 58
[2] Patent: US5468742, 1995, A
[3] Patent: US5480879, 1996, A
[4] Oriental Journal of Chemistry, 2013, vol. 29, # 1, p. 241 - 246

(S,S)-2,8-Diazabicyclo[4,3,0]nonane Preparation Products And Raw materials

Raw materials

Preparation Products

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(S,S)-2,8-Diazabicyclo[4,3,0]nonane Suppliers

China 316 Europe 2 Germany 1 India 9 South Korea 1 United Kingdom 3 United States 17 Global 349

Wuhan pushida biotechnology co., Ltd

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shilang(zhuoli group)-pharma(nanjing) co.,ltd.

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View Lastest Price from (S,S)-2,8-Diazabicyclo[4,3,0]nonane manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (S,S)-2,8-Diazabicyclo[4,3,0]nonane 151213-42-2
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-10-29

Moxin Chemicals

Product: Moxifloxacin Impurity 151213-42-2
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98
Supply Ability: 100000000
Release date: 2024-12-10

Shaanxi Dideu New Materials Co. Ltd

Product: (S,S)-2,8-Diazabicyclo[4,3,0]nonane 151213-42-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-01

151213-42-2, (S,S)-2,8-Diazabicyclo[4,3,0]nonaneRelated Search:

3-Ethyl-6,7,8,9-tetrahydro-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one 3-pentylisoindolin-1-one Acotiamide INT (4aS,7aS)-1-methyloctahydro-1H-pyrrolo[3,4-b]pyridine 3-ethyl-9-hydroxy-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone) Indene 7-Aminocephalosporanic acid 6-Aminopenicillanic acid Ribostamycin sulfate DBU N-NONANE CIS-OCTAHYDROPYRROLO[3,4-B]PYRIDINE 9-methyl-3,9-diazedicyclo(4,2,1)nonane (S,S)-2,8-Diazabicyclo[4,3,0]nonane Moxifloxacin Methyl Ester 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester 3-Quinolinecarboxylic acid, 7-[(4aS,7aS)-1-(2-carboxyethyl)octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-

[S,S]-2,8-Diazabicyclo[4.3.0]Nonane98%

(S,S)-2,8-Diazabicyclo[4,3,0]onoane

(S,S)-2,8-DIAZABICYCLO[4,3,0]NONANE [FOR MOXIFLOXACIN]

(1S,6S)-2,8-Diazacyclo[4,3,0]nonane ,99%

Moxifloxacin Intermediate 1

2,8-Diazabicyclo[4.3.0]nonane,Cis-Octahydropyrrolo[3,4-B]Pyridine

cis-Octahydropyrrolo[3,4-b]pyridine/(R,R)-2,8-Diazabicyclo[4,3,0]nonane

(1R,6R)-2,8-Diazabicyclo[4,3,0]nonane

(S,S)-2,8-diazabycyclo[4,3,0]-nonane

1H-Pyrrolo[3,4-b]pyridine,octahydro-, (4aR,7aR)-

(S,S)-2,8-Diazabicyclo[4,3,0]nonane###2,8-Diazabicyclo[4.3.0]nonane###CIS-OCTAHYDROPYRROLO[3,4-B]PYRIDINE

(S,S)-2,8-DIAZABICYCLO{4,3,0} NONANE (AS PER INVOICE)

(R,R)-2,8-DIAZABICYCLO[4,3,0]NONANE

[S,S]-2,8-DIAZABICYCLO[4,3,0]NONANE

CIS-OCTAHYDROPYRROLO[3,4-B]PYRIDINE

(S,S)-2,8-Diazabicylco(4,3,0)Nonane

MOXIFLOXACIN INTERMEDIATES

Moxifloxacin side chain

Moxifloxacin Impurity S2

(S,S)-2,8-Diazabicyclo[4,3,0]nonane in stock Factory

Moxifloxacin intermediate compound 1

Moxifloxacin-23

Moxifloxacin (R,R)-Nonane

(S,S)-2,8-Diazabicyclo[4,3,0]

(4aR,7aR)-1H-octahydropyrrolo[3,4-b]pyridine

(S,S)-2,8-Diazabicyclo[4,3,0]nonane(NF)

(1R,6R)-2,8-Diazabicyclo[4.3.0]nonane (Technical Grade)

(S,S)-2,8-Diazabicyclo Nonane

Azilsartan medoxomil impurity274

(4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine (Moxifloxacin Impurity)

Moxifloxacin Impurity 37(See C3D-2318)

Moxifloxacin Nonane

151213-42-2

151213-42-0

Heterocycle-Pyridine series

pharmacetical

API intermediates

pharmaceutical intermediates