4-METHYL-2-NITROBENZYLALCOHOL
- Product Name
- 4-METHYL-2-NITROBENZYLALCOHOL
- CAS No.
- 81335-87-7
- Chemical Name
- 4-METHYL-2-NITROBENZYLALCOHOL
- Synonyms
- 4-METHYL-2-NITROBENZYLALCOHOL;2-AMINO-4-METHYLBENZYL ALCOHOL;Benzenemethanol, 2-amino-4-methyl-;(2-Amino-4-methyl-phenyl)-methanol
- CBNumber
- CB6667311
- Molecular Formula
- C8H11NO
- Formula Weight
- 137.18
- MOL File
- 81335-87-7.mol
4-METHYL-2-NITROBENZYLALCOHOL Property
- Boiling point:
- 295.4±25.0 °C(Predicted)
- Density
- 1.126±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 14.35±0.10(Predicted)
- Appearance
- White to off-white Solid
N-Bromosuccinimide Price
- Product number
- A898608
- Product name
- (2-Amino-4-methylphenyl)methanol
- Packaging
- 500mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- FA142363
- Product name
- (2-Amino-4-methylphenyl)methanol
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FA142363
- Product name
- (2-Amino-4-methylphenyl)methanol
- Packaging
- 1g
- Price
- $143
- Updated
- 2021/12/16
- Product number
- FA142363
- Product name
- (2-Amino-4-methylphenyl)methanol
- Packaging
- 2g
- Price
- $248
- Updated
- 2021/12/16
- Product number
- FA142363
- Product name
- (2-Amino-4-methylphenyl)methanol
- Packaging
- 5G
- Price
- $495
- Updated
- 2021/12/16
4-METHYL-2-NITROBENZYLALCOHOL Chemical Properties,Usage,Production
Synthesis
22996-24-3
81335-87-7
General procedure for the synthesis of (2-amino-4-methylphenyl)methanol from (4-methyl-2-nitrophenyl)methanol: General method: (4-methyl-2-nitrophenyl)methanol (12) was dissolved in ethanol (concentration 0.2 M) and palladium/carbon catalyst (10% w/w, 5 mol%) was added. The reaction mixture was stirred for 1 h at room temperature under hydrogen atmosphere. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and washed several times with ethyl acetate. The filtrate was concentrated under reduced pressure to obtain the crude product aniline, which was subsequently precipitated in a solvent mixture of petroleum ether and ethyl acetate (9:1, v/v). The precipitate was filtered and the solid was washed three times with a solvent mixture of the same ratio to give the final target product (2-amino-4-methylphenyl)methanol (11).
References
[1] Synlett, 2017, vol. 28, # 14, p. 1724 - 1728
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5810 - 5831
4-METHYL-2-NITROBENZYLALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
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