1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE
Uses- Product Name
- 1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE
- CAS No.
- 13078-13-2
- Chemical Name
- 1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE
- Synonyms
- TIMTEC-BB SBB003158;N-(M-Tolyl)piperazine diHCl;1-(M-TOLYL)PIPERAZINE DI HCL;M-TOLYLPIPERAZINE HYDROCHLORIDE;N-(3-Methylphenyl)piperazinedi2HCl;1-(m-Tolyl)piperazine hydrochloride;N-(M-TOLYL)PIPERAZINE DIHYDROCHLORIDE;1-(M-TOLYL)PIPERAZINE DIHYDROCHLORIDE;1-(3-Methylphenyl)piperazine dihydrochloride;N-(3-Methylphenyl)piperazine dihydrochloride
- CBNumber
- CB6675567
- Molecular Formula
- C11H16N2.2ClH
- Formula Weight
- 249.18
- MOL File
- 13078-13-2.mol
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Property
- Melting point:
- 195-202 °C
- form
- powder to crystal
- color
- White to Almost white
- CAS DataBase Reference
- 13078-13-2(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- Risk Statements
- 36/37/38-24-22
- Safety Statements
- 45-36/37/39-26
- HS Code
- 2933.59.8000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- R261858
- Product name
- 1-M-TOLYL-PIPERAZINE, DIHYDROCHLORIDE
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $28.6
- Updated
- 2023/06/20
- Product number
- T1310
- Product name
- N-(m-Tolyl)piperazine Dihydrochloride
- Purity
- >96.0%(T)
- Packaging
- 10g
- Price
- $192
- Updated
- 2024/03/01
- Product number
- T536563
- Product name
- 1-(m-Tolyl)piperazineDihydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 43384
- Product name
- N-(m-Tolyl)piperazinedihydrochloride,≥96%(Assaybytitration)
- Purity
- ≥96%(Assaybytitration)
- Packaging
- 10G
- Price
- $224.18
- Updated
- 2021/12/16
- Product number
- 8362AL
- Product name
- N-(m-Tolyl)piperazine Dihydrochloride
- Packaging
- 10g
- Price
- $334
- Updated
- 2021/12/16
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Chemical Properties,Usage,Production
Uses
1-(3-methylphenyl)piperazine dihydrochloride is a piperazine derivative and can be used as a pharmaceutical intermediate.
Synthesis
In a 100 ml flask, diethanolamine (10 g) was dissolved in chloroform (40 ml), and a chloroform (20 ml) solution of dichlorosulfoxide (2.6 ml) was added slowly and dropwise at room temperature. Reacted for 7h, the reaction was complete, spun dry, chloroform was added additionally, spun dry again and the dichlorosulfoxide was evaporated to dryness. It was dried to give 14 g of white solid (??-chloroethyl)amine hydrochloride in 85% yield, mp: 214.1-215.2??C (literature value > 215-216??C).
1.58g (10mmol) of IX was added to 10ml of n-butanol with 1mol of aniline derivative and reacted at 180??C for 30min in microwave. at the end of the reaction it was allowed to stand and cooled to precipitate crystals. The filter cake was washed with a small amount of dichloromethane and dried under vacuum to obtain white crystals of 1-(3-methylphenyl)piperazine dihydrochloride in 45-54% yield.
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9888
- Advantage
- 59
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11705
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55