L-Canavanine

Product Name: L-Canavanine
CAS No.: 543-38-4
Chemical Name: L-Canavanine
Synonyms: AI352153;canavanin;AI3 52153;AI3-52153;canavanine;L-CANAVANINE;FSBIGDSBMBYOPN-VKHMYHEASA-N;(L) Canavanine,(L)Canavanine;(+)-O-(Guanidino)-L-homoserine;2-amino-4-(guanidinooxy)butyricacid
CBNumber: CB6679318
Molecular Formula: C5H12N4O3
Formula Weight: 176.17
MOL File: 543-38-4.mol

More

Less

L-Canavanine Property

Melting point:: 184°
alpha: D20 +7.9° (c = 3.2)
Boiling point:: 307.78°C (rough estimate)
Density: 1.3685 (rough estimate)
refractive index: 1.7900 (estimate)
storage temp.: 2-8°C
solubility: H₂O: <100 mg/mL
form: powder
pka: pK1: 2.50(+2);pK2: 6.60(+1);pK3: 9.25(0) (25°C)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36
WGK Germany: 3
RTECS: ES7002000
Hazardous Substances Data: 543-38-4(Hazardous Substances Data)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C1625
Product name: L-Canavanine
Purity: ≥98% (TLC), powder, from Canavalia ensiformis
Packaging: 100mg
Price: $135
Updated: 2024/03/01

Sigma-Aldrich

Product number: C1625
Product name: L-Canavanine
Purity: ≥98% (TLC), powder, from Canavalia ensiformis
Packaging: 1g
Price: $673
Updated: 2024/03/01

Sigma-Aldrich

Product number: C1625
Product name: L-Canavanine
Purity: ≥98% (TLC), powder, from Canavalia ensiformis
Packaging: 250mg
Price: $179.2
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FC162286
Product name: L-Canavanine
Packaging: 100mg
Price: $180
Updated: 2021/12/16

AK Scientific

Product number: X6876
Product name: L-Canavanine
Packaging: 250mg
Price: $255
Updated: 2021/12/16

More

Less

L-Canavanine Chemical Properties,Usage,Production

Uses

NO synthase inhibitor

Definition

ChEBI: A non-proteinogenicL-alpha-amino acid that is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. Although structurally related to L-arginine, it is non-proteinoge ic.

Biochem/physiol Actions

Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.

Purification Methods

Crystallise S-canavanine from absolute EtOH or aqueous EtOH. [Tomiyama J Biol Chem 111 48 1935 gave pK9.25 (COOH), pK 7.4 (guanidinium), pK 11.5 (NH4+), Gulland & Morris J Chem Soc 763 1935,(±) Frankel et al. J Chem Soc 3127 1963, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2622-2628 1961, Beilstein 4 III 1636, 4 IV 3188.]

L-Canavanine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

L-Canavanine Suppliers

China 28 Switzerland 1 United Kingdom 1 United States 3 Global 33

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12990
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8073
Advantage: 58

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7892
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9175
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

Jiangsu Hongmin Pharmaceutical Co., Ltd.

Tel: 18221292452
Email: fannieliu@glschina.com
Country: China
ProdList: 6799
Advantage: 58

543-38-4, L-CanavanineRelated Search:

JACK BEANS L-Canavanine FMOC-L-CNV(PMC)-OH L-Canavanine sulfate L-CANALINE BASE

2-amino-4-(guanidinooxy)butyricacid

canavanin

canavanine

o-((aminoiminomethyl)amino)-l-homoserin

o-((aminoiminomethyl)amino)-l-homoserine

o-[(aminoiminomethyl)amino]homoserine

L-CANAVANINE

L-ALPHA-AMINO-GAMMA-[GUANIDINOOXY]-N-BUTYRIC ACID

L-CANAVANINE FREE BASE FROM JACK BEANSCR YSTALLINE

L-Homoserine, O-(aminoiminomethyl)amino-

l-α-amino-γ-(guanidinooxy)-n-butyric acid

2-amino-4-(diaminomethylideneamino)oxy-butanoic acid

L-canavanine free base from jack beans*crystallin

BUTYRICACID,2-AMINO-4-(GUANIDINOOXY)-L-

(+)-O-(Guanidino)-L-homoserine

(S)-2-Amino-4-(guanidinooxy)butyric acid

(S)-2-aMino-4-(guanidinooxy)butanoic acid

L-CANAVANINE FREE BASE FROM JACK BEA

FSBIGDSBMBYOPN-VKHMYHEASA-N

L-Canavanine >=98% (TLC), powder, from Canavalia ensiformis

AI3 52153

AI352153

AI3-52153

(L) Canavanine,(L)Canavanine

543-38-4

H2NCNHNHOCH2CH2CHNH2COOH

C5H12N4O3

BioChemical

Biochemicals and Reagents

Nitric Oxide Synthase (iNOS)

L to O

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme

Enzymes, Inhibitors, and Substrates