4-Chlorophenyl isocyanate

Product Name: 4-Chlorophenyl isocyanate
CAS No.: 104-12-1
Chemical Name: 4-Chlorophenyl isocyanate
Synonyms: 1-Chloro-4-isocyanatobenzene;P-CHLOROPHENYL ISOCYANATE;PCPI;4-Chlorphenylisocyanate;PARA CHLOROPHENYL ISOCYANATE;pcic;4-Chlorophenyl isocy;p-Chlorfenylisokyanat;4-Chlorphenylisocyanat;chlorophenylisocyanate
CBNumber: CB6680525
Molecular Formula: C7H4ClNO
Formula Weight: 153.57
MOL File: 104-12-1.mol

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4-Chlorophenyl isocyanate Property

Melting point:: 26-29 °C (lit.)
Boiling point:: 203-204 °C (lit.)
Density: 1.2 g/mL at 25 °C (lit.)
vapor pressure: 30Pa at 20℃
refractive index: n20/D 1.5618(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
solubility: Chloroform (Slightly)
form: Crystalline Solid
color: White to yellow
Odor: sharp irritating odor
Water Solubility: DECOMPOSES
Sensitive: Moisture Sensitive/Lachrymatory
BRN: 386235
LogP: 3.12 at 22℃
CAS DataBase Reference: 104-12-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1-chloro-4-isocyanato-(104-12-1)
EPA Substance Registry System: p-Chlorophenyl isocyanate (104-12-1)

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Safety

Hazard Codes: T+,T,C
Risk Statements: 25-26-37/38-41-42-52/53
Safety Statements: 23-26-28-36/37/39-45-61-38-37/39-28A-22
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: NQ8575000
F: 10-19-21
Hazard Note: Toxic/Corrosive/Lachrymatory/Moisture Sensitive
TSCA: Yes
HazardClass: 6.1
PackingGroup: II
HS Code: 29291090
Hazardous Substances Data: 104-12-1(Hazardous Substances Data)
Toxicity: mammal (species unspecified),LC50,inhalation,53mg/m3 (53mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 11(4), Pg. 23, 1967.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H330Fatal if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 152277
Product name: 4-Chlorophenyl isocyanate
Purity: 98%
Packaging: 5g
Price: $54.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 152277
Product name: 4-Chlorophenyl isocyanate
Purity: 98%
Packaging: 100g
Price: $116
Updated: 2024/03/01

Alfa Aesar

Product number: A14966
Product name: 4-Chlorophenyl isocyanate, 98%
Packaging: 5g
Price: $21.65
Updated: 2024/03/01

Alfa Aesar

Product number: A14966
Product name: 4-Chlorophenyl isocyanate, 98%
Packaging: 25g
Price: $41.65
Updated: 2024/03/01

Alfa Aesar

Product number: A14966
Product name: 4-Chlorophenyl isocyanate, 98%
Packaging: 100g
Price: $104.65
Updated: 2024/03/01

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4-Chlorophenyl isocyanate Chemical Properties,Usage,Production

Chemical Properties

white to yellow crystalline solid

Uses

4-Chlorophenyl isocyanate is used in the preparation of isothiocyanates. Aryl isocyanates undergo [2+2] cycloaddition reactions with dihydrofuran to give bicyclic ?-lactams in high yield.

Uses

4-Chlorophenyl isocyanate was used in the preparation of isothiocyanates.

Synthesis Reference(s)

The Journal of Organic Chemistry, 34, p. 3200, 1969 DOI: 10.1021/jo01262a089

General Description

Colorless to yellow liquid or crystals. Used as an intermediate in pesticide and pharmaceutical manufacture.

Reactivity Profile

Isocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

Safety Profile

Poison by ingestion and inhalation. Unspecified human systemic effects. A severe eye and moderate skin irritant. A flammable liquid when exposed to heat or flame. Dangerous, can explode on distillation. When heated to decomposition it emits toxic fumes of Cl-, CN-, and NOx.

Purification Methods

Purify the isocyanate by recrystallisation from pet ether (b 30-40o) or better by fractional distillation. TOXIC irritant. [Beilstein 12 H 616, 12 III 1376, 12 IV 1213.]

4-Chlorophenyl isocyanate Preparation Products And Raw materials

Raw materials

PHOSGENE 4-Chloroaniline

Preparation Products

Diflubenzuron

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4-Chlorophenyl isocyanate Suppliers

Belgium 4 Canada 2 China 237 China Hong Kong 1 Czech Republic 4 Europe 2 Germany 7 India 19 Italy 1 Japan 4 Poland 1 South Africa 1 South Korea 2 Switzerland 3 The Netherlands 1 Ukraine 1 United Kingdom 16 United States 33 Global 339

TCI Chemicals (India) Pvt. Ltd.

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Alfa Aesar

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Paushak Limited

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Spectrochem Private Limited

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OCEAN TRADING CORPORATION

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View Lastest Price from 4-Chlorophenyl isocyanate manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Chlorophenyl isocyanate 104-12-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.%
Supply Ability: 10 ton
Release date: 2024-08-21

Henan Bao Enluo International TradeCo.，LTD

Product: 4-Chlorophenyl isocyanate 104-12-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000tons
Release date: 2023-08-17

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Chlorophenyl isocyanate 104-12-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-10

104-12-1, 4-Chlorophenyl isocyanateRelated Search:

Propyl isocyanate 3,5-Dichlorophenyl isocyanate Chlorosulfonyl isocyanate Chlorobenzene 1,3-Bis(isocyanatomethyl)benzene Benzyl isocyanate BENZOYL ISOCYANATE ISOCYANIC ACID Hexyl isocyanate Isocyanatocyclohexane Isocyanic acid 3,4-dichlorophenyl ester METHYLIDYNETRI-P-PHENYLENE TRIISOCYANATE ISOCYANATE Phenyl isocyanate 2,4-Dichlorophenyl isocyanate 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 4-CHLORO-2-NITROPHENYL ISOCYANATE 2,4,6-TRICHLOROPHENYL ISOCYANATE

1-chloro-4-isocyanato-benzen

1-Chloro-4-isocyanatobenzene

1-Chloro-4-isocyanato-benzene

4-chloroisocyanatobenzene

4-Chloro-iso-cyanatobenzene

4-Chlorphenylisocyanate

benzene,1-chloro-4-isocyanato

Phenylisocyanate,4-chloro-

P-CHLOROPHENYL ISOCYANATE

PARA CHLOROPHENYL ISOCYANATE

ISOCYANIC ACID 4-CHLOROPHENYL ESTER

4-ISOCYANATO CHLOROBENZENE

4-CHLOROPHENYL ISOCYANATE

4-Chlorphenylisocyanat

4-Chlorobenzenisocyanate

P-CHLOROPHENYL ISOCYANATE (PCPI)

4-Chlorophenyl isocyanate, 98% 100GR

4-Chlorophenyl isocyanate, 98% 25GR

4-Chlorophenyl isocyanate,98%

4-Chlorophenyl isocyanate,pract.

4-Chlorophenyl isocy

4-Chlorophenyl isocyate

4-Chlorophenyl isocyanate 98%

benzene,1-chloro-4-isocyanato-

chlorophenylisocyanate

chlorophenylisocyanate(non-specificname)

isoacyanicacid,p-chlorophenylester

Isocyanic acid, p-chlorophenyl ester

isocyanicacid,p-chlorophenylester

p-Chlorfenylisokyanat

p-chlorfenylisokyanat(czech)

pcic

PCPI

4-ChlorophenylIsocyanate&gt

104-12-1

104-21-1

203-176-9

104-21-1

ClC6H4NCO

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