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Deslanoside

Product Name
Deslanoside
CAS No.
17598-65-1
Chemical Name
Deslanoside
Synonyms
Desace;Desaci;cedilanidd;sediranido;eslanoside;DESLANOSIDE;DESLANOSIDUM;deslanatoside;Deslanoside C;Deslanoside RS
CBNumber
CB6683081
Molecular Formula
C47H74O19
Formula Weight
943.08
MOL File
17598-65-1.mol
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Deslanoside Property

Melting point:
220-235°C
alpha 
D20 +12° (c = 1.084 in 75% alc)
Boiling point:
732.1°C (rough estimate)
Density 
1.1255 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
2-8°C
solubility 
DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
form 
Solid
pka
12.89±0.70(Predicted)
color 
White to off-white
CAS DataBase Reference
17598-65-1(CAS DataBase Reference)
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Safety

Risk Statements 
23/25-33
Safety Statements 
1-22-45
RIDADR 
2811
HS Code 
2938900000
Toxicity
cat,LD50,intravenous,230ug/kg (0.23mg/kg),"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 190, 1963.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D0600000
Product name
Deslanoside
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
160 mg
Price
$153
Updated
2025/07/31
Sigma-Aldrich
Product number
1173009
Product name
Deslanoside
Packaging
200mg
Price
$373
Updated
2025/07/31
Sigma-Aldrich
Product number
D0600000
Product name
Deslanoside
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
d0600000
Price
$150
Updated
2024/03/01
TRC
Product number
D288320
Product name
DesacetyllanatosideC
Packaging
100mg
Price
$1200
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001913
Product name
DEACETYL-LANOTOSIDE C
Purity
95.00%
Packaging
5MG
Price
$830.91
Updated
2021/12/16
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Deslanoside Chemical Properties,Usage,Production

Chemical Properties

Solution S is clear (2.2.1) and colourless (2.2.2, Method II).

Uses

Cardiotonic.

Definition

ChEBI: Deslanoside is a cardenolide glycoside that is lanatoside C with the acetoxy group replaced by a hydroxy group. It has a role as an anti-arrhythmia drug, a cardiotonic drug, a metabolite and an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. It is a 14beta-hydroxy steroid, a 12beta-hydroxy steroid, a cardenolide glycoside and a tetrasaccharide derivative.

brand name

Cedilanid-D (Novartis).

General Description

Deslanoside is a white crystalline powder; odourless, with a bitter taste; hygroscopic. It is slightly soluble in methanol, very slightly soluble in ethanol, and practically insoluble in water or chloroform.

Biological Activity

Deslanoside is a cardiac glycoside that has been found in D. lanata.[1] It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg.[2] Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.​

References

[1] Koren, G., and Soldin, S.J. Cardiac glycosides. Clin. Lab. Med. 7(3), 587-606 (1987).
[2] Ghani, M.F., and Smith, J.R. The effectiveness of magnesium chloride in the treatment of ventricular tachyarrhythmias due to digitalis intoxication. Am. Heart J. 88(5), 621-626 (1974).
[3] MALGORZATA KLYS  Adam G. Determination of deslanoside in antemortem and postmortem specimens. Unusual case report[J]. Forensic science international, 1990, 45 3: Pages 231-238. DOI:10.1016/0379-0738(90)90179-3.

Deslanoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Deslanoside Suppliers

ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from Deslanoside manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Deslanoside 17598-65-1
Price
US $0.00-0.00/KG
Min. Order
25KG
Purity
0.99
Supply Ability
5000kg/month
Release date
2024-04-24
Career Henan Chemical Co
Product
Deslanoside 17598-65-1
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1kg,5kg,50kg
Release date
2020-01-18

17598-65-1, DeslanosideRelated Search:


  • cedilanidd
  • deacetyl-lanatoside
  • desacetyllanatosidec
  • descetyldigilanidec
  • deslanatoside
  • sediranido
  • Deslanoside (JP14/USP)
  • Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
  • Deacetylanatoside C
  • De-O-acetyllanatoside C
  • Desace
  • Desaci
  • Deslanatoside C
  • Deslanoside C
  • Lanatoside C, deacetyl- (6CI, 7CI, 8CI)
  • Purpurea glycoside C
  • Desacetyl-Lanatosid C
  • Deacetyl-lanotoside C
  • 4-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-3-[(2R,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5H-furan-2-one
  • Deslanoside (100 mg)
  • DEACETYLLANATOSIDE C
  • DESLANOSIDE
  • DESLANOSIDUM
  • Deslanoside CRS
  • Deslanoside RS
  • eslanoside
  • Deslanoside USP/EP/BP
  • 17598-65-1 Deslanoside
  • Deslanoside (1173009)
  • Methyl Salicylate Impurity 8
  • Deslanoside, 10 mM in DMSO
  • 17598-65-1
  • C47H74O19
  • Cardioglycosides & Glycosides