ChemicalBook > CAS DataBase List > 12(S)-HPEPE
12(S)-HPEPE
- Product Name
- 12(S)-HPEPE
- CAS No.
- 103239-14-1
- Chemical Name
- 12(S)-HPEPE
- Synonyms
- 12(S)-HPEPE;HDMYXONNVAOHFR-UOLHMMFFSA-N;12(S)-HpEPE(solution in ethanol);12(S)-hydroperoxy-5(Z),8(Z),10(E),14(Z),17(Z)-EPA;12S-HYDROPEROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID;5,8,10,14,17-Eicosapentaenoic acid, 12-hydroperoxy-, (5Z,8Z,10E,12S,14Z,17Z)-
- CBNumber
- CB6687498
- Molecular Formula
- C20H30O4
- Formula Weight
- 334.45
- MOL File
- 103239-14-1.mol
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12(S)-HPEPE Property
- storage temp.
- Store at -20°C
- solubility
- 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 42550
- Product name
- 12(S)-HpEPE
- Purity
- ≥96%
- Packaging
- 25μg
- Price
- $201
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 42550
- Product name
- 12(S)-HpEPE
- Purity
- ≥96%
- Packaging
- 50μg
- Price
- $362
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 42550
- Product name
- 12(S)-HpEPE
- Purity
- ≥96%
- Packaging
- 100μg
- Price
- $642
- Updated
- 2024/03/01
AHH
- Product number
- MT-14825
- Product name
- 12(S)-Hpepe
- Purity
- 98%
- Packaging
- 0.0001g
- Price
- $410
- Updated
- 2021/12/16
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12(S)-HPEPE Chemical Properties,Usage,Production
Description
12(S)-
Uses
12(S)-HPEPE is a lipoxygenase product and an intermediate metabolite that leads to downregulation of PGHS-2 and has potential anti-inflammatory activity. 12(S)-HPEPE reduces interleukin 1h (IL-1h)-induced PGHS-2 expression in human lung microvascular endothelial cells[1].
Definition
ChEBI: 12(S)-HpEPE is a 12-HPEPE in which the hydroperoxy group at positions 12 has S-configuration. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a 12(S)-HpEPE(1-).
References
[1] Ait-Said F, et al. Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. Biochim Biophys Acta. 2003 Feb 20;1631(1):77-84. DOI:10.1016/s1388-1981(02)00358-x
12(S)-HPEPE Preparation Products And Raw materials
Raw materials
Preparation Products
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103239-14-1, 12(S)-HPEPERelated Search:
(Z,Z)-3,6-NONADIEN-1-OL
12(S)-HPEPE
12(S)-HEPE
(+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID