ChemicalBook > CAS DataBase List > HUMAN IL-11
HUMAN IL-11
Description Source Background- Product Name
- HUMAN IL-11
- Chemical Name
- HUMAN IL-11
- Synonyms
- AGIF;IL-11;RHIL-11;HUMAN AGIF;HUMAN IL-11;IL-11, HUMAN;INTERLEUKIN 11;REC IL-11 (HUMAN);HUMAN INTERLEUKIN-11;INTERLEUKIN-11, HUMAN
- CBNumber
- CB6699369
- Formula Weight
- 0
- MOL File
- Mol file
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HUMAN IL-11 Property
- storage temp.
- −20°C
- form
- lyophilized powder
- color
- off-white to yellow
- biological source
- mouse
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SRP3072
- Product name
- IL-11 human
- Purity
- recombinant, expressed in <I>E. coli</I>, ≥98% (SDS-PAGE), suitable for cell culture
- Packaging
- 10 μg
- Price
- $356
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SAB1411909
- Product name
- ANTI-IL11 antibody produced in mouse
- Purity
- clone 3C6, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100 μg
- Price
- $541
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- I2406
- Product name
- Interleukin-11 human
- Purity
- >97% (SDS-PAGE), recombinant, expressed in baculovirus infected <I>Sf</I>21 cells, lyophilized powder, suitable for cell culture
- Packaging
- 5 μg
- Price
- $330.5
- Updated
- 2025/07/31
Usbiological
- Product number
- I8433-03
- Product name
- Interleukin 11
- Packaging
- 25ug
- Price
- $340
- Updated
- 2021/12/16
Usbiological
- Product number
- 155347
- Product name
- Interleukin 11
- Packaging
- 10ug
- Price
- $350
- Updated
- 2021/12/16
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HUMAN IL-11 Chemical Properties,Usage,Production
Biological Activity
Interleukin 11 (IL11) stimulates tumorigenesis in conjunction with angiogenesis of the primary tumor and of metastatic progenies at distant organs. IL-11 signaling is considered as a rate-limiting step for the tumorigenesis in the mucosa of the gastrointestinal tract. Thus, inhibition of IL-11 signaling can be considered as an emerging therapeutic strategy for various cancers. In addition, this protein also performs a protective role by increasing platelet recovery and inflammatory responses, in sepsis patients with thrombocytopenia. Mutation in the gene increases the risk of susceptibility to Hirschsprung disease and multiple sclerosis (MS).
Description
Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton.
The IL-11 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
IL11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). IL-11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
HUMAN IL-11 Preparation Products And Raw materials
Raw materials
Preparation Products
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