3-BENZYLOXYBROMOBENZENE
- Product Name
- 3-BENZYLOXYBROMOBENZENE
- CAS No.
- 53087-13-1
- Chemical Name
- 3-BENZYLOXYBROMOBENZENE
- Synonyms
- Metaraminol Impurity 14;oxy-3-bromobenzene;3-Benzyloxybromobenzen;3-BENZYLOXYBROMOBENZENE;Metaraminol Impurity 29;Metaraminol Impurity 62;3-BROMOPHENYL BENZYL ETHER;1-Bromo-3-benzyloxybenzene;BENZYL 3-BROMOPHENYL ETHER;1-BENZYLOXY-3-BROMOBENZENE
- CBNumber
- CB6700025
- Molecular Formula
- C13H11BrO
- Formula Weight
- 263.13
- MOL File
- 53087-13-1.mol
3-BENZYLOXYBROMOBENZENE Property
- Melting point:
- 57-60 °C
- Boiling point:
- 333.5±17.0 °C(Predicted)
- Density
- 1.382±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Solid
- color
- White
- InChI
- InChI=1S/C13H11BrO/c14-12-7-4-8-13(9-12)15-10-11-5-2-1-3-6-11/h1-9H,10H2
- InChIKey
- HVWZMGZBJCJDOX-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=CC(OCC2=CC=CC=C2)=C1
- CAS DataBase Reference
- 53087-13-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,N
- Risk Statements
- 36/37/38-50/53-43-41
- Safety Statements
- 26-36/37/39-50/53-43-41-61-60
- RIDADR
- UN 3077 9/PG 3
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29093090
N-Bromosuccinimide Price
- Product number
- 668419
- Product name
- 3-Benzyloxybromobenzene
- Purity
- 96%
- Packaging
- 10g
- Price
- $84.5
- Updated
- 2023/06/20
- Product number
- 668419
- Product name
- 3-Benzyloxybromobenzene
- Purity
- 96%
- Packaging
- 50g
- Price
- $216
- Updated
- 2023/06/20
- Product number
- B2307
- Product name
- 1-Benzyloxy-3-bromobenzene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $34
- Updated
- 2025/07/31
- Product number
- B2307
- Product name
- 1-Benzyloxy-3-bromobenzene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $134
- Updated
- 2025/07/31
- Product number
- B291410
- Product name
- 1-(Benzyloxy)-3-bromobenzene
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
3-BENZYLOXYBROMOBENZENE Chemical Properties,Usage,Production
Chemical Properties
Whitetolightyellowcrystalpowde
Synthesis
591-20-8
100-44-7
53087-13-1
1. Anhydrous potassium carbonate (37.32 g, 270 mmol) and benzyl chloride (11.50 mL, 99 mmol) were added to a suspension of anhydrous ethanol (300 mL) containing m-bromophenol (15.57 g, 90 mmol) under nitrogen protection. The reaction mixture was heated to reflux for 4 hours. After completion of the reaction, the ethanol was removed by vacuum filtration and evaporation. The residue was extracted with ethyl acetate (EtOAc) and the combined organic layers were washed sequentially with water, 2 M NaOH solution, saturated brine and 2 M HCl solution, dried over anhydrous sodium sulfate (Na2SO4) and concentrated to give the yellow solid product 3-benzyloxybromobenzene (22.02 g, 93%). 2. To a 250 mL two-necked round-bottomed flask, protected by nitrogen, were added dry magnesium chips (2.18 g, 90 mmol) and trace iodine, equipped with two rubber septa and stirred. Anhydrous tetrahydrofuran (THF, 40 mL) solution of 3-benzyloxybromobenzene (15.79 g, 60 mmol) was slowly added through a syringe and kept at reflux. After addition, stirring was continued at reflux for 5 hours. After the reaction mixture was cooled to -30°C, anhydrous THF (60 mL) solution of trimethyl borate (9.36 g, 90 mmol) was slowly added. After addition, the mixture was stirred at room temperature overnight, followed by treatment with saturated ammonium chloride (NH4Cl) solution and continued stirring at room temperature for 1 hour. THF was removed by rotary evaporation, the aqueous layer was extracted with EtOAc, dried over anhydrous Na2SO4, filtered and concentrated to give a yellow crude product. The crude product was purified by recrystallization in water to give white solid target product (7.53 g, 55%).
References
[1] Journal of Materials Chemistry, 2010, vol. 20, # 15, p. 3069 - 3078
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 5, p. 1044 - 1054
[3] Journal of Medicinal and Pharmaceutical Chemistry, 1962, vol. 5, p. 752 - 762
[4] Patent: US5447656, 1995, A
[5] Patent: EP838461, 1998, A2
3-BENZYLOXYBROMOBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
3-BENZYLOXYBROMOBENZENE Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 3-BENZYLOXYBROMOBENZENE manufacturers
- Product
- 3-BENZYLOXYBROMOBENZENE 53087-13-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-07
- Product
- 3-BENZYLOXYBROMOBENZENE 53087-13-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25