ChemicalBook > CAS DataBase List > POBN
POBN
- Product Name
- POBN
- CAS No.
- 66893-81-0
- Chemical Name
- POBN
- Synonyms
- POBN;Butylpyridyloxidenitrone;-(4-pyridyl-1-oxide)nitrone;PYRIDYLOXIDE t-BUTYLNITRONE;N-tert-Butyl-α4-Pyridyl-1-oxide-tert-butyl Nitrone;A-(4-PYRIDYL-N-OXIDE-N-TERT-BUTYLNITRONE;N-TERT-BUTYL-A-(4-PYRIDYL)NITRONEN-OXIDE;N-tert-Butyl-α-(4-pyridyl-1-oxide)nitrone;α-(4-pyridyl n-oxide)-n-tert-butylnitrone
- CBNumber
- CB6702751
- Molecular Formula
- C10H14N2O2
- Formula Weight
- 194.23
- MOL File
- 66893-81-0.mol
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POBN Property
- Melting point:
- 183-185 °C(lit.)
- Boiling point:
- 330.68°C (rough estimate)
- Density
- 1.1444 (rough estimate)
- refractive index
- 1.5000 (estimate)
- storage temp.
- room temp
- solubility
- water: soluble10mg/mL, clear, colorless to faintly yellow
- form
- White to off-white or colorless crystalline solid.
- pka
- 0.76±0.53(Predicted)
- color
- White to Light yellow
- BRN
- 1453764
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29333999
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 215430
- Product name
- α-(4-Pyridyl N-oxide)-N-tert-butylnitrone
- Purity
- 99%
- Packaging
- 1g
- Price
- $625
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- P9271
- Product name
- α-(4-Pyridyl N-oxide)-N-tert-butylnitrone
- Purity
- ~95%
- Packaging
- 1g
- Price
- $62
- Updated
- 2023/06/20
TCI Chemical
- Product number
- B1735
- Product name
- N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $224
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B1735
- Product name
- N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitrone
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $673
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20623
- Product name
- POBN
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $40
- Updated
- 2024/03/01
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POBN Chemical Properties,Usage,Production
Chemical Properties
white to pale yellow crystalline powder
Uses
Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.
Uses
POBN is a cell permeable hydrophilic spin trap for in vitro studies. It is a water soluble analog of PBN with low paramagnetic impurities and does not require any further purification. POBN has also also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide.
POBN Preparation Products And Raw materials
Raw materials
Preparation Products
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66893-81-0, POBNRelated Search:
1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine
4,4'-DIPYRIDYL DISULFIDE
4-Picoline-N-oxide
4-Pyridinealdoxime
isonicotinaldehyde oxime 1-oxide
POBN