ChemicalBook > CAS DataBase List > 2-Deoxy-L-ribose

2-Deoxy-L-ribose

Product Name
2-Deoxy-L-ribose
CAS No.
18546-37-7
Chemical Name
2-Deoxy-L-ribose
Synonyms
-ribose;2-Deoxy-L;L-2-Deoxyribose;2-DEOXY-L-RIBOSE;Xylose Impurity 19;2-DEOXY-L-RIBOSE 99%;2-Deoxy-L-ribose,99%;2-Deoxy-L-ribose ,98%;Brivudine Impurity 22;L-ERYTHRO-PENTOFURANOSE
CBNumber
CB6704755
Molecular Formula
C5H10O4
Formula Weight
134.13
MOL File
18546-37-7.mol
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2-Deoxy-L-ribose Property

Melting point:
69-72°C
alpha 
57 º (c=0.9 H2O after 24h)
Boiling point:
167.23°C (rough estimate)
Density 
1.0590 (rough estimate)
refractive index 
1.4050 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
13.58±0.20(Predicted)
color 
Light Yellow to Pale Beige
optical activity
[α]/D 54.0±2.0°, 24 hr, c = 1 in H2O
CAS DataBase Reference
18546-37-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-37/39-36-26
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
75617
Product name
2-Deoxy-L-ribose
Purity
≥97.0% (TLC)
Packaging
5g
Price
$306
Updated
2024/03/01
Sigma-Aldrich
Product number
75617
Product name
2-Deoxy-L-ribose
Purity
≥97.0% (TLC)
Packaging
1g
Price
$62.7
Updated
2023/06/20
TRC
Product number
D252050
Product name
2-Deoxy-L-ribose
Packaging
5G
Price
$150
Updated
2021/12/16
Usbiological
Product number
292960
Product name
2-Deoxy-L-ribose
Packaging
5g
Price
$319
Updated
2021/12/16
Matrix Scientific
Product number
162247
Product name
2-Deoxy-L-erythro-pentopyranose
Packaging
0.500g
Price
$320
Updated
2021/12/16
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2-Deoxy-L-ribose Chemical Properties,Usage,Production

Chemical Properties

white to light beige crystalline powder

Uses

2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose (D252000) which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.

Definition

ChEBI: 2-deoxy-L-arabinose is a deoxypentose. It is functionally related to a L-arabinose.

Production Methods

The provides the synthetic process of 2-Deoxy-L-ribose comprising the steps of; (A) protection step in which aldehyde group of 2-deoxy-D-ribose is protected in the form of acetal. 2-deoxy-l-O-alkyl-D-ribopyranoside is prepared by the reaction of 2-deoxy-D-ribose with alcohol in the presence of acid; (B) activation step in which 3 -and 4-OH groups of 2-deoxy-D-ribose are activated. 2-deoxy-l-O-alkyl- 3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-1-O-alkyl-3,4-di-(arylsulfonyl)-D-ribose is prepared by reaction of the above 2-deoxy-l-O-alkyl-D-ribose with organic sulfonylhalide for activation of 3- and 4-OH; (C) inversion step in which stereochemistry of 3- and 4-OH groups is changed. Reaction of the above 2-deoxy-l- O-alkyl-3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-l-O-alkyl-3,4-di-(arylsulfonyl)- D-ribose with a metal salt of organic acid leads to 2-deoxy-L-ribose derivatives of which stereochemistry of 3- and 4-OH is different from the corresponding 2-deoxy-D- ribose derivatives; (D) deprotection step in which 2-deoxy-L-ribose is prepared by consecutive reactions of the step (C) products with acid and base.

Purification Methods

Crystallise 2-deoxy--L-ribose from diethyl ether. It can also be purified by dissolving the ribose (7.3g) in EtOAc (3L) by reflux, decanting from any insoluble mate

2-Deoxy-L-ribose Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Deoxy-L-ribose Suppliers

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View Lastest Price from 2-Deoxy-L-ribose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Deoxy-L-ribose 18546-37-7
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
98%min
Supply Ability
100kgs
Release date
2021-09-16
Henan Bao Enluo International TradeCo.，LTD
Product
2-Deoxy-L-ribose 18546-37-7
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-08-16
Henan Aochuang Chemical Co.,Ltd.
Product
2-Deoxy-L-ribose 18546-37-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29

18546-37-7, 2-Deoxy-L-riboseRelated Search:

Ribose D-Ribose .alpha.-Deoxy-D-ribos DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* ARABINIC ACID QS 21 4-NITROPHENYL-ALPHA-L-ARABINOFURANOSIDE MUCIC ACID CALCIUM L-ARABONATE 1-ACETYL-2,3,5-TRI-O-BENZOYL-B-L-RIBOFURANOSE ROSARIN Ginsenoside Rc beta-D-Ribofuranose 1,2,3,5-tetraacetate HAMAMELITANNIN 1-CHLORO-3,5-DI-(P-CHLOROBENZOYL)-2-DEOXY-D-RIBOSE,88+%,1-CHLORO-3,5-DI(4-CHLORBENZOYL)-2-DEOXY-D-RIBOSE,1-CHLORO-3,5-DIPARACHLOROBENZOYL-2-DEOXY-D-RIBOSE 1-(ALPHA)-CHLORO-3,5-DI-O-(P-TOLUOYL)-2-DEOXY-D-RIBOSE METHYL 2-DEOXY-D-RIBOSE,1-O-METHYL-2-DEOXY-D-RIBOSE 2-DEOXY-D-RIBOSE ANILINE

  • 2-DEOXY-L-RIBOSE
  • L-ERYTHRO-PENTOFURANOSE
  • 2-DEOXY-L-RIBOSE 99%
  • L-erythro-Pentose, 2-deoxy-
  • (3R,4S)-3,4,5-Trihydroxypentanal
  • L-threo-2-deoxy-pentose
  • 2-Deoxy-L-ribose,99%
  • 2-Deoxy-L-ribose ,98%
  • tetrahydrofuran-2,4-diol
  • (4R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2,4-diol
  • 2-Deoxy-L
  • -ribose
  • 2-Deoxy-L-ribose USP/EP/BP
  • L-2-Deoxyribose
  • Brivudine Impurity 22
  • Xylose Impurity 19
  • 18546-37-7
  • 6704-75-5
  • 8546-37-7
  • C5H10O4
  • Carbohydrates
  • Pharmaceutical Raw Materials
  • john's