L-Ribose
- Product Name
- L-Ribose
- CAS No.
- 24259-59-4
- Chemical Name
- L-Ribose
- Synonyms
- L-RIBOSE;Ribose;L - RNA;L-D-Ribose;L-(+)-Ribos;L-(+)-RIBOSE;z052L-Ribose;L-Ribose >L-Ribose ,98%;L-PLUS-RIBOSE
- CBNumber
- CB8256607
- Molecular Formula
- C5H10O5
- Formula Weight
- 150.13
- MOL File
- 24259-59-4.mol
L-Ribose Property
- Melting point:
- 81-82 °C(lit.)
- alpha
- 20 º (c=2,water)
- Boiling point:
- 191.65°C (rough estimate)
- Density
- 1.1897 (rough estimate)
- refractive index
- 20 ° (C=1, H2O)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 12.22(at 25℃)
- color
- White to Off-White
- Water Solubility
- Soluble in water (100 mg/ml).
- BRN
- 1723084
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m1/s1
- InChIKey
- PYMYPHUHKUWMLA-MROZADKFSA-N
- SMILES
- O=C[C@H]([C@H]([C@H](CO)O)O)O
- CAS DataBase Reference
- 24259-59-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-37-36-36/38
- Safety Statements
- 24/25-36-26-37/39
- WGK Germany
- 3
- RTECS
- 246-110-4
- F
- 3-10
- HS Code
- 29400000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R4377
- Product name
- L-(+)-Ribose
- Packaging
- 1g
- Price
- $345.8
- Updated
- 2025/07/31
- Product number
- R0068
- Product name
- L-Ribose
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $16
- Updated
- 2025/07/31
- Product number
- R0068
- Product name
- L-Ribose
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- R0068
- Product name
- L-Ribose
- Purity
- >98.0%(HPLC)
- Packaging
- 25g
- Price
- $120
- Updated
- 2025/07/31
- Product number
- R417505
- Product name
- L-Ribose
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
L-Ribose Chemical Properties,Usage,Production
Chemical Properties
white crystals or powder
Uses
L-[1-13C]ribose is a compound useful in organic synthesis.
Uses
It is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate.
Definition
A monosaccharide; a component of RNA.
Definition
ribose: A monosaccharide, C5H10O5, rarely occurring free in nature but important as a component of RNA (ribonucleic acid). Its derivative deoxyribose, C5H10O4, is equally important as a constituent of DNA (deoxyribonucleic acid), which carries the genetic code in chromosomes.
Biosynthesis
L-ribose is the enantiomer of D-ribose, which occurs naturally. It is a building block of many novel nucleotide analogue anti-viral drugs. Bio-production of L-ribose relies on a two-step reaction: (i) conversion of L-arabinose to L-ribulose by the catalytic action of L-arabinose isomerase (L-AI) and (ii) conversion of L-ribulose to L-ribose by the catalytic action of L-ribose isomerase (L-RI, EC 5.3.1.B3) or mannose-6-phosphate isomerase (MPI, EC 5.3.1.8, alternately named as phosphomannose isomerase). Among the two enzymes, L-RI is a rare enzyme discovered in 1996 by Professor Izumori's group, whereas MPI is an essential enzyme in metabolic pathways in humans and microorganisms[1].
Synthesis
A method for converting inexpensive, naturally occurring D-ribose into L-ribose is by interconverting the hydroxy group at Cl and the hydroxymethyl group at C5. L-Ribose is prepared from D-ribose by (a) forming a hydroxy-protected D-ribose, (b) reducing the hydroxy-protected D-ribose to a protected tetrol, (c) converting the tetrol to a tetraester, such as a tetraacetate; (d) hydrolyzing the protecting group to form a hydroxymethyl tetraester; (e) oxidizing the hydroxymethyl group to form a tetraester aldehyde; and (f) hydrolysing the ester groups to yield L-ribose.
References
[1] M. Helanto. “Biotechnological production of l-ribose from l-arabinose.” Applied Microbiology and Biotechnology 83 1 (2009): 77–83.
L-Ribose Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-Ribose manufacturers
- Product
- Ribose 24259-59-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 5000kg/month
- Release date
- 2023-01-06
- Product
- Ribose 24259-59-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-04
- Product
- Ribose 24259-59-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26