ChemicalBook > CAS DataBase List > L-Ribose

L-Ribose

Product Name
L-Ribose
CAS No.
24259-59-4
Chemical Name
L-Ribose
Synonyms
L-RIBOSE;Ribose;L - RNA;L-D-Ribose;L-(+)-Ribos;L-(+)-RIBOSE;z052L-Ribose;L-Ribose >L-Ribose ,98%;L-PLUS-RIBOSE
CBNumber
CB8256607
Molecular Formula
C5H10O5
Formula Weight
150.13
MOL File
24259-59-4.mol
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L-Ribose Property

Melting point:
81-82 °C(lit.)
alpha 
20 º (c=2,water)
Boiling point:
191.65°C (rough estimate)
Density 
1.1897 (rough estimate)
refractive index 
20 ° (C=1, H2O)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
12.22(at 25℃)
color 
White to Off-White
Water Solubility 
Soluble in water (100 mg/ml).
BRN 
1723084
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChI
InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m1/s1
InChIKey
PYMYPHUHKUWMLA-MROZADKFSA-N
SMILES
O=C[C@H]([C@H]([C@H](CO)O)O)O
CAS DataBase Reference
24259-59-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-37-36-36/38
Safety Statements 
24/25-36-26-37/39
WGK Germany 
3
RTECS 
246-110-4
F 
3-10
HS Code 
29400000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R4377
Product name
L-(+)-Ribose
Packaging
1g
Price
$345.8
Updated
2025/07/31
TCI Chemical
Product number
R0068
Product name
L-Ribose
Purity
>98.0%(HPLC)
Packaging
1g
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
R0068
Product name
L-Ribose
Purity
>98.0%(HPLC)
Packaging
5g
Price
$40
Updated
2025/07/31
TCI Chemical
Product number
R0068
Product name
L-Ribose
Purity
>98.0%(HPLC)
Packaging
25g
Price
$120
Updated
2025/07/31
TRC
Product number
R417505
Product name
L-Ribose
Packaging
1g
Price
$50
Updated
2021/12/16
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L-Ribose Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Uses

L-[1-13C]ribose is a compound useful in organic synthesis.

Uses

It is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate.

Definition

A monosaccharide; a component of RNA.

Definition

ribose: A monosaccharide, C5H10O5, rarely occurring free in nature but important as a component of RNA (ribonucleic acid). Its derivative deoxyribose, C5H10O4, is equally important as a constituent of DNA (deoxyribonucleic acid), which carries the genetic code in chromosomes.

Biosynthesis

L-ribose is the enantiomer of D-ribose, which occurs naturally. It is a building block of many novel nucleotide analogue anti-viral drugs. Bio-production of L-ribose relies on a two-step reaction: (i) conversion of L-arabinose to L-ribulose by the catalytic action of L-arabinose isomerase (L-AI) and (ii) conversion of L-ribulose to L-ribose by the catalytic action of L-ribose isomerase (L-RI, EC 5.3.1.B3) or mannose-6-phosphate isomerase (MPI, EC 5.3.1.8, alternately named as phosphomannose isomerase). Among the two enzymes, L-RI is a rare enzyme discovered in 1996 by Professor Izumori's group, whereas MPI is an essential enzyme in metabolic pathways in humans and microorganisms[1].

Synthesis

A method for converting inexpensive, naturally occurring D-ribose into L-ribose is by interconverting the hydroxy group at Cl and the hydroxymethyl group at C5. L-Ribose is prepared from D-ribose by (a) forming a hydroxy-protected D-ribose, (b) reducing the hydroxy-protected D-ribose to a protected tetrol, (c) converting the tetrol to a tetraester, such as a tetraacetate; (d) hydrolyzing the protecting group to form a hydroxymethyl tetraester; (e) oxidizing the hydroxymethyl group to form a tetraester aldehyde; and (f) hydrolysing the ester groups to yield L-ribose.

References

[1] M. Helanto. “Biotechnological production of l-ribose from l-arabinose.” Applied Microbiology and Biotechnology 83 1 (2009): 77–83.

L-Ribose Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Ribose Suppliers

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View Lastest Price from L-Ribose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ribose 24259-59-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
5000kg/month
Release date
2023-01-06
Hebei Chuanghai Biotechnology Co., Ltd
Product
Ribose 24259-59-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-04
Henan Aochuang Chemical Co.,Ltd.
Product
Ribose 24259-59-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26

24259-59-4, L-RiboseRelated Search:

Ribonucleic acid L-Arabinopyranose RIBOSE, D-(-)- DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS* ribonucleic acid for injection 6-O-(TRIISOPROPYLSILYL)-D-GALACTAL CYCLIC CARBONATE D-TALOSE DNA polymeraseⅠfrom E.coli METHYL 2-DEOXY-D-RIBOSE DnaseⅠ Deoxycytidine triphosphate trisodium salt RIBONIC ACID POLY ADP-RIBOSE POLYMERASE 3'-GMP DISODIUM SALT CAD（Caspase-Activated Deoxyribonuclease） DNA，plasmid pSP64 2'-DEOXYURIDINE 5'-TRIPHOSPHATE SODIUM SALT 1,3,5-Tri-O-benzoyl-D-ribofuranose

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