ChemicalBook > CAS DataBase List > 3-Hydroxypropionic acid

3-Hydroxypropionic acid

Product Name
3-Hydroxypropionic acid
CAS No.
503-66-2
Chemical Name
3-Hydroxypropionic acid
Synonyms
3-HYDROXYPROPANOIC ACID;HYDRACRYLIC ACID;Propanoic acid, 3-hydroxy-;CHEBI:33404;beta-lacticacid;.beta.-Lacticacid;ethylenelacticacid;RARECHEM AL BO 0193;2-deoxy-glycericaci;2-deoxy-Glycericacid
CBNumber
CB6711580
Molecular Formula
C3H6O3
Formula Weight
90.08
MOL File
503-66-2.mol
More
Less

3-Hydroxypropionic acid Property

Melting point:
16.8°C (estimate)
Boiling point:
212°C (rough estimate)
Density 
1.066 g/mL at 25 °C
refractive index 
1.4489
storage temp. 
2-8°C
solubility 
Ethanol, Methanol, Water
pka
4.51(at 25℃)
form 
Colourless Solution
color 
Colorless to Almost colorless
Water Solubility 
270.1g/L(25 ºC)
InChI
InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)
InChIKey
ALRHLSYJTWAHJZ-UHFFFAOYSA-N
SMILES
C(O)(=O)CCO
CAS DataBase Reference
503-66-2(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36/37/39-39
HS Code 
29181990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
792659
Product name
3-Hydroxypropionic acid, 30%solution in water
Packaging
1G
Price
$61.3
Updated
2023/06/20
TCI Chemical
Product number
H0297
Product name
3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L)
Packaging
10g
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
H0297
Product name
3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L)
Packaging
25g
Price
$369
Updated
2024/03/01
TRC
Product number
H961903
Product name
3-HydroxypropionicAcid,Approx30%inWater(withvaryingamountsof3,3''-OxydipropanoicAcid)
Packaging
500mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
9018AF
Product name
3-Hydroxypropionicacid,(ca.30%inWater,ca.3.6mol/L)
Packaging
5g
Price
$85
Updated
2021/12/16
More
Less

3-Hydroxypropionic acid Chemical Properties,Usage,Production

Description

3-Hydroxypropionic acid (3-HP) is considered as a potential building block either for organic synthesis or high performance polymers.It is a 3-carbon carboxylic acid, structural isomer of lactic acid, which naturally exists in some thermophilic archaea and bacteria. This organic compound has been pointed out by the US Department of Energy as a promising biomass derivate, which could potentially be used for the production of high added-value chemicals like1,3-propanediol, acrylic acid, acrylamide, and bioplastics.
Being 3-HP a commercially valuable, important platform chemical, researches have been conducted about its production on commercial scale, mainly from renewable sources. The biological production of 3-HP from glycerol and glucose, both based on microbial fermentation, are among the main routes studied. More specifically, research activities have been devoted to goals such as identifying novel biochemical pathways, metabolic engineering of microbial strains for the production of 3-HP, and improvements of cultivation techniques to increase 3-HP production titers.
Despite intense research efforts, there are still important bottlenecks for cost efficient, large scale biological production of 3-Hydroxypropionic Acid.

Uses

3-Hydroxypropionic Acid induces gene expressions and also functions as a reagent for industrial application.

Uses

A three carbon non-chiral compound, 3-Hydroxypropionic acid can be used as a building block for industrial chemicals.

Definition

ChEBI: A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group.

Production Methods

β-Hydroxypropionic acid can be prepared by alkaline hydration of acrylic acid or by treatment of ethylene chlorohydrin with sodium cyanide, followed by hydrolysis of the resulting β-hydroxypropionitrile. It is also readily obtained by hydrolysis of the commercially important and easily accessible compound β-propiolactone.

3-Hydroxypropionic acid Preparation Products And Raw materials

Raw materials

3-Hydroxypropionitrile Diethyl ether Sodium hydroxide Syrup, NF Magnesium sulfate Sulfuric acid

Preparation Products

TERT-BUTYL 3-HYDROXYPROPIONATE
More
Less

3-Hydroxypropionic acid Suppliers

Americas 1 Belgium 1 China 154 Europe 1 Germany 6 India 5 Japan 2 United Kingdom 11 United States 26 Global 207
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
6637
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50471
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169097
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
Advantage
64
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8613162137806 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9747
Advantage
57
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1937
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel
027-8866 0053/88660577/88660578
Fax
027-8899 1911
Country
China
ProdList
1076
Advantage
55
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9352
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1303
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17981
Advantage
56
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Mashilabs (Shanghai) Co.,Ltd.
Tel
021-00000000 19916721580
Fax
QQ：3154870176
Email
info@mashilabs.com
Country
China
ProdList
4115
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653713 17501653715
Email
xingui2022@126.com
Country
China
ProdList
10033
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9798
Advantage
50
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ：245797092
Email
market@gianthx.com
Country
China
ProdList
4512
Advantage
56
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Zhengzhou AnMusi Chemical Products Co., Ltd.
Tel
0371-55289822 18737195735
Fax
QQ：2370407954
Email
2370407954@qq.com
Country
China
ProdList
2000
Advantage
55
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Shanghai Aoyeah Chemical Technology Co., Ltd.
Tel
021-021-64367138 15900495324
Fax
QQ：2504753890
Email
sales@aoyeahchem.com
Country
China
ProdList
203
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9974
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
More
Less

View Lastest Price from 3-Hydroxypropionic acid manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
3-Hydroxypropionic acid 503-66-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-10
Honest Joy Holdings Limited
Product
3-Hydroxypropionic acid 503-66-2
Price
US $0.00/KG
Min. Order
1KG
Purity
97.2%
Supply Ability
100 tons
Release date
2022-02-18
Career Henan Chemical Co
Product
3-HYDROXYPROPIONIC ACID 503-66-2
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-15

503-66-2, 3-Hydroxypropionic acidRelated Search:

[3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) Sulfamide FAMOTIDINE RELATED COMPOUND B 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 3-Chloropropiononitrile 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER Famotidine 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoylpropanamidine FaMotidine Acid IMpurity N-DesaMinosulfonyl-N-cyano FaMotidine FaMotidine Acid IMpurity Methyl Ester 3-HYDROXYPROPIONAMIDE FaMotidine AMide IMpurity Famotidine EP Impurity A

  • .beta.-Hydroxypropionicacid
  • .beta.-Lacticacid
  • beta-lacticacid
  • ethylenelacticacid
  • Glycericacid,2-deoxy-
  • Hydracrylic-acid-ethylenelacticacid
  • Propionicacid,3-hydroxy-
  • β-Hydroxypropionsαure
  • HYDRACRYLIC ACID
  • 3-HYDROXYPROPANOIC ACID
  • 3-HYDROXYPROPIONIC ACID
  • RARECHEM AL BO 0193
  • 2-deoxy-glycericaci
  • 2-deoxy-Glycericacid
  • 3-Hydroxypropansαure
  • 3-Hydroxypropioicacid
  • 3-hydroxy-propionicaci
  • beta-hydroxypropionicacid
  • 3-HYDROXYPROPIONIC ACID (BETA-)(CA. 30% IN WATER)
  • 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6mol/L)
  • 3-Hydrocypropanoic acid
  • 3-Hydroxypropionicacid,30%inwater
  • 3-HYDROXYPROPANOICACID(30%SOLUTIONINWATER)
  • 3-Hydroxypropionic acid ,98%
  • 3-Hydroxypropanoic acid, 30% aqueous solution
  • (contains varying aMounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water, ca. 3.6Mol/L)
  • 3-Hydroxypropionic Acid&nbsp
  • 3-Hydroxypropanoic acid 95%
  • 3-Hydroxypropionic acid, Hydracrylic acid
  • 3-Hydroxypropanoic acid solution
  • 3-Hydroxypropionic Acid (ca. 30% in Water, ca. 3.6mol/L)
  • CHEBI:33404
  • Propanoic acid, 3-hydroxy-
  • 3-Hydroxypropanoic acid (30% in water)
  • 3-Hydroxypropionic acid, 30% solution in H2O
  • 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid)
  • 3-Hydroxypropinic acid
  • 3-Hydroxypropionic Acid, Approx 30% in Water (with varying amounts of 3,3'-Oxydipropanoic Acid)
  • Famotidine Impurity 18
  • "3-Hydroxypropionic acid, approx 30% in water"
  • 3-Hydroxypropionic Acid, 30wt.% in H2O
  • 3-Hydroxypropanoic acid(contains varying amounts of 3,3'-Oxydipropionic Acid) (ca. 30% in Water)
  • 3-Hydroxypropionic acid（ca. 30% in Water）
  • 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid)
  • Famotidine Impurity 37
  • 503-66-2
  • HOCH2CH2COOH
  • 蠅-Hydroxycarboxylic Acids
  • 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides
  • omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
  • omega-Hydroxycarboxylic Acids
  • Carboxylic Acids
  • Aliphatics
  • Carboxylic Acids