MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH

Product Name: MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH
CAS No.: 189696-20-6
Chemical Name: MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH
Synonyms: MCA-DEVDAPK (DNP);MCA-DEVDAPK(DNP)-OH;CASPASE-3 SUBSTRATE (MCA);CPP32 Fluorogenic Substrate III;CASPASE-3 SUBSTRATE III, FLUOROGENIC;MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP);MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH;MCA-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-COOH;7-methoxycoumarin-4-acetyl-asp-glu-*val-asp-ala-P;MCA-DEVDAPK(DNP)-OH;CPP32 FLUOROGENIC SUBSTRATE III
CBNumber: CB6715311
Molecular Formula: C50H62N10O22
Formula Weight: 1155.08
MOL File: 189696-20-6.mol

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MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Property

Boiling point:: 1561.2±65.0 °C(Predicted)
Density: 1.455±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: Formic Acid: 1 mg/ml
form: Lyophilized powder
pka: 3.67±0.21(Predicted)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M1169
Product name: 7-Methoxycoumarin-4-acetyl-Asp-Glu-Val-Asp-Ala-Pro-(2,4-dinitrophenyl)Lys
Packaging: 0.5mg
Price: $361
Updated: 2023/01/07

Cayman Chemical

Product number: 24563
Product name: Mca-DEVDAPK(Dnp)-OH
Purity: ≥95%
Packaging: 500μg
Price: $128
Updated: 2024/03/01

Cayman Chemical

Product number: 24563
Product name: Mca-DEVDAPK(Dnp)-OH
Purity: ≥95%
Packaging: 1mg
Price: $243
Updated: 2024/03/01

AK Scientific

Product number: 6266DU
Product name: (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-3-Carboxy-2-[[(2S)-2-[[(2S)-4-carboxy-2-[[(2S)-3-carboxy-2-[[2-(7-methoxy-2-oxochromen-4-yl)acetyl]amino]propanoyl]amino]butanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-6-(2,4-dinitroanilino)hexanoicacid
Packaging: 1mg
Price: $348
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0115377
Product name: 7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-VAL-ASP-ALA-PRO-(2,4-DINITROPHENYL)LYS
Purity: 95.00%
Packaging: 0.5MG
Price: $768.65
Updated: 2021/12/16

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MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Chemical Properties,Usage,Production

Description

Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify caspase-3 activity.

Uses

Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3[1].

IC 50

Caspase-3

References

[1] Fertig Georg. Method for the detection of the apoptosis activated cysteine protease Caspase 3 by specific antibody-binding and fluorescence enzyme assay. EP0955377A1

Sequene

Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Suppliers

China 23 Switzerland 1 United Kingdom 1 United States 6 Global 31

SIGMA-RBI

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Country: Switzerland
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189696-20-6, MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OHRelated Search:

N-(2,4-DINITROPHENYL)-6-AMINOHEXANOIC ACID AC-DEVD-CHO CHEMBRDG-BB 7932577 MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH

MCA-DEVDAPK (DNP)

MCA-DEVDAPK(DNP)-OH

CASPASE-3 SUBSTRATE III, FLUOROGENIC

CASPASE-3 SUBSTRATE (MCA)

7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-VAL-ASP-ALA-PRO-(2,4-DINITROPHENYL)-LYS

7-methoxycoumarin-4-acetyl-asp-glu-*val-asp-ala-P

7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-*VAL- ASP-ALA-PRO

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS: DNP[MCA-DEVDAP-K: DNP]

CPP32 Fluorogenic Substrate III

MCA-DEVDAPK(DNP)-OH;CPP32 FLUOROGENIC SUBSTRATE III

L-Lysine,N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-

L-Lysine, N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)- (9CI)

MCA-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-COOH

189696-20-6

C50H62N10O22

Substrates

BioChemical

Caspase 3

Caspases

Cell Biology

Cell Signaling and Neuroscience

Apoptosis and Cell Cycle

Caspase 3

Caspase 3Caspase Inhibitors and Substrates

Caspase Substrates

Caspases

Substrates