1,4-DIOXANE-D8 Property

Melting point:

12°C

Boiling point:

99 °C(lit.)

Density 

1.129 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4198(lit.)

Flash point:

54 °F

storage temp. 

Flammables area

form 

Liquid

Specific Gravity

1.13

Water Solubility 

Miscible with water.

Sensitive 

Hygroscopic

BRN 

1307286

CAS DataBase Reference

17647-74-4(CAS DataBase Reference)

EPA Substance Registry System

1,4-Dioxane-d8 (17647-74-4)

Safety

Hazard Codes 

F,Xn,T

Risk Statements 

11-19-36/37-40-39/23/24/25-23/24/25-66

Safety Statements 

16-36/37-45-7-46-9

RIDADR 

UN 1165 3/PG 2

WGK Germany 

3

F 

3-10

HazardClass 

3

PackingGroup 

II

HS Code 

28459000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

1,4-DIOXANE-D8 Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

1,4-Dioxane-d{8} is used as a solvent in nuclear magnetic resonance (NMR) spectroscopy and acts as a stabilizer for 1,1,1-trichloroethane.

General Description

1,4-Dioxane-d₈ is a deuterated derivative of 1,4-dioxane. It has an isotopic purity of 99atom%D. It is a standard purity solvent suitable for routine NMR analyses (conducted at ambient temperatures where quality is less critical). It is widely employed as a deuterated standard. It participates as a surrogate standard during the activated carbon SPE (solid-phase extraction) and GC-MS-SIM (gas chromatography-mass spectrometry (GC-MS) in selected ion monitoring (SIM) mode) quantification of 1,4-dioxane in drinking water.