ChemicalBook > CAS DataBase List > 4-Benzyloxy-3-methylbenzeneboronic acid

4-Benzyloxy-3-methylbenzeneboronic acid

Product Name: 4-Benzyloxy-3-methylbenzeneboronic acid
CAS No.: 338454-30-1
Chemical Name: 4-Benzyloxy-3-methylbenzeneboronic acid
Synonyms: oxy-3-methyL;AKOS BRN-0646;4-BENZYLOXY-3-METHYLPHENYLBORONIC ACID;(4-BENZYLOXY-3-METHYL)BENZENEBORONIC ACID;4-Benzyloxy-3-methylbenzeneboronicacid96%;4-Benzyloxy-3-methylbenzeneboronic acid 96%;(3-methyl-4-phenylmethoxyphenyl)boronic acid;Boronic acid, B-[3-methyl-4-(phenylmethoxy)phenyl]-;4-Benzyloxy-3-methylbenzeneboronic acid(contains varying amounts of Anhydride);4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)
CBNumber: CB6723345
Molecular Formula: C14H15BO3
Formula Weight: 242.08
MOL File: 338454-30-1.mol

Less

4-Benzyloxy-3-methylbenzeneboronic acid Property

Melting point:: 102-106
Boiling point:: 431.6±55.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: powder to crystal
pka: 8.74±0.17(Predicted)
color: White to Almost white
CAS DataBase Reference: 338454-30-1(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
HazardClass: IRRITANT
HS Code: 29310095

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5169
Product name: 4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 1g
Price: $65
Updated: 2025/07/31

TCI Chemical

Product number: B5169
Product name: 4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $192
Updated: 2025/07/31

TRC

Product number: B410903
Product name: 4-Benzyloxy-3-methylphenylboronicacid
Packaging: 1g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 035555
Product name: 4-Benzyloxy-3-methylphenylboronic acid
Purity: 97%
Packaging: 1g
Price: $59
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB149392
Product name: 4-Benzyloxy-3-methylphenylboronicacid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Less

4-Benzyloxy-3-methylbenzeneboronic acid Chemical Properties,Usage,Production

Uses

suzuki reaction

Synthesis

338454-32-3

338454-30-1

General procedure for the synthesis of 4-benzyloxy-3-methylbenzeneboronic acid from 2-benzyloxy-5-bromotoluene: 4-bromo-1-benzyloxy-2-methylbenzene (6.9 g, 25 mmol) was dissolved in molecularly sieve-dried tetrahydrofuran (37.5 mL) and the solution was cooled to -78 °C. A n-hexane solution of 1.6 M n-butyllithium (17 mL, 27.5 mmol) was added slowly and dropwise over a period of 30 min, keeping the reaction temperature from exceeding -70 °C. After continued stirring at this temperature for 10 min, trimethyl borate (8.3 mL, 75 mmol) was added dropwise over 25 min below -70 °C. The reaction mixture was allowed to warm slowly to room temperature and stirred overnight. The reaction mixture was then cooled to 0 °C and aqueous 1 N hydrochloric acid was added dropwise. The reaction mixture was diluted with water and ethyl acetate to separate the organic and aqueous phases, and the aqueous phase was then extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated aqueous sodium chloride solution, dried with magnesium sulfate, filtered and concentrated. 4-Benzyloxy-3-methylphenylboronic acid 3.95 g (yield 65%) was obtained as a white powder. Mass spectrum (ISN): 301.2 (M-H)-.

References

[1] Patent: US6821980, 2004, B1. Location in patent: Page column 28
[2] Chemistry - A European Journal, 2000, vol. 6, # 20, p. 3821 - 3837

4-Benzyloxy-3-methylbenzeneboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-Benzyloxy-3-methylbenzeneboronic acid Suppliers

Americas 1 China 85 Europe 3 Germany 4 India 4 Japan 1 Russia 1 United Kingdom 8 United States 15 Global 122

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9986
Advantage: 58

Shanghai Rong Lin Medical Technology Co., Ltd.

Tel: 18602194589
Email: lincy-110@163.com
Country: China
ProdList: 863
Advantage: 58

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Wuhan Chemwish Technology Co.， Ltd

Tel: 027-67849912
Fax: 027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 9148
Advantage: 60

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Suzhou Future Chemical Technology Co., Ltd.

Tel: 13921981169
Fax: -
Email: ftchem2016@163.com
Country: China
ProdList: 464
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10109
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing YakeLun Pharmaceutical Co., Ltd.

Tel: 025-66096098 3165145969
Fax: QQ3165145969
Email: sales@accoronpharm.com
Country: China
ProdList: 3924
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai HongMin Pharmaceutical Co., Ltd.

Tel: 13651987816
Fax: -
Email: hongminpharm@163.com
Country: China
ProdList: 2326
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Nanjing holy chemical co., LTD

Tel: 19951936396
Email: 1815156226@qq.com
Country: China
ProdList: 2947
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

TCI Chemicals

Tel: 021-67121386, 800-988-0390
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 5391
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
Advantage: 58

Shanghai Jiange Chemical Co., Ltd.

Tel: 15921040873
Email: 1434142450@qq.com
Country: CHINA
ProdList: 7649
Advantage: 58

Jinan ponder chemical co. LTD

Tel: 0531-0000
Email: thinklifescience@163.com
Country: China
ProdList: 19689
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Wuhan Chemwish Technology Co., Ltd

Tel: 027-67849912
Email: sales@chemwish.com
Country: CHINA
ProdList: 10821
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Country: China
ProdList: 5743
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Mainchem Co., Ltd.

Tel: --
Fax: --
Email: sarah@mainchem.com
Country: China
ProdList: 6547
Advantage: 58

Weihai Huaixin Biotechnology Co., Ltd

Tel: 15662379806
Email: 845423637@qq.com
Country: China
ProdList: 1656
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002 18367600069;
Email: zhejia01@163.com
Country: China
ProdList: 8887
Advantage: 58

Zhengzhou Deyuankai Chemical Co., LTD

Tel: 17837139533
Email: 1165412154@qq.com
Country: China
ProdList: 7740
Advantage: 58

Hangzhou Hongxi Biomedical Technology Co., LTD

Tel: 18989489206
Email: hoxipharm@163.com
Country: China
ProdList: 4921
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50751
Advantage: 58

Shanghai Tengjun Biotechnology Co. LTD

Tel: 19821570922
Email: angela@labgogo.com
Country: China
ProdList: 9896
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Less

View Lastest Price from 4-Benzyloxy-3-methylbenzeneboronic acid manufacturers

Career Henan Chemical Co

Product: 4-Benzyloxy-3-methylbenzeneboronic acid 338454-30-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg; 5kg; 100kg
Release date: 2019-07-03

338454-30-1, 4-Benzyloxy-3-methylbenzeneboronic acidRelated Search:

2-(BENZYLOXY)-5-METHYLPHENYLBORONIC ACID 4-Benzyloxy-2-methylphenylboronic acid 4-(2'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN& 2-[4-Benzyloxy-3-(trifluoromethyl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane 4-Benzyloxy-3,5-dimethylphenylboronic acid 2-Benzyloxy-5-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile (2-(benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(pyrrolidin-1-yl)methanone 4-(3'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN& 4-BENZYLOXY-3-CHLORO-5-METHYLPHENYLBORONIC ACID 4-BENZYLOXY-3-FORMYLPHENYLBORONIC ACID 4-Benzyloxy-3-methylbenzeneboronic acid 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane 4-(4'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN& 2-Benzyloxy-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile 2-[4-Benzyloxy-3-(1,3-dioxan-2-yl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane 2-[4-Benzyloxy-3-(1,3-dioxan-2-yl)phenyl]-4,4,6-trimethyl-1,3,2-dioxaborinane

4-Benzyloxy-3-methylbenzeneboronic acid 96%

AKOS BRN-0646

4-Benzyloxy-3-methylbenzeneboronicacid96%

(4-BENZYLOXY-3-METHYL)BENZENEBORONIC ACID

4-BENZYLOXY-3-METHYLPHENYLBORONIC ACID

4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)

(3-methyl-4-phenylmethoxyphenyl)boronic acid

oxy-3-methyL

Boronic acid, B-[3-methyl-4-(phenylmethoxy)phenyl]-

4-Benzyloxy-3-methylbenzeneboronic acid(contains varying amounts of Anhydride)

338454-30-1

blocks

BoronicAcids

Boronic acid