BMY 45778

Product Name: BMY 45778
CAS No.: 152575-66-1
Chemical Name: BMY 45778
Synonyms: BMY 45778;BMY 45778 >=98% (HPLC);[3-(4,5-DIPHENYL[2,4'-BIOXAZOL]-5'-YL)PHENOXY]ACETIC ACID;Acetic acid, 2-[3-(4,5-diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]-
CBNumber: CB6723653
Molecular Formula: C26H18N2O5
Formula Weight: 438.43
MOL File: 152575-66-1.mol

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BMY 45778 Property

Boiling point:: 659.9±65.0 °C(Predicted)
Density: 1.298±0.06 g/cm3(Predicted)
storage temp.: room temp
solubility: ≥67.6 mg/mL in DMSO
form: powder
pka: 3.10±0.10(Predicted)
color: white to beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BM0032
Product name: BMY 45778
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $402
Updated: 2022/05/15

Tocris

Product number: 1442
Product name: BMY 45778
Purity: ≥99%(HPLC)
Packaging: 50
Price: $587
Updated: 2021/12/16

TRC

Product number: B596418
Product name: BMY 45778
Packaging: 2.5mg
Price: $175
Updated: 2021/12/16

ApexBio Technology

Product number: B6741
Product name: BMY 45778
Packaging: 10mg
Price: $213
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: KIN0008616
Product name: BMY 45778
Purity: 95.00%
Packaging: 10MG
Price: $709.46
Updated: 2021/12/16

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BMY 45778 Chemical Properties,Usage,Production

Uses

BMY 45778 is an agonist for IP receptor to up-regulate the expression of C?/EBPβ and C?/EBPδ.

Definition

ChEBI: BMY 45778 is a bisoxazole. It has a role as a partial prostacyclin agonist.

Biological Activity

Non-prostanoid prostacyclin mimetic that acts as a partial agonist at IP 1 prostacyclin receptors. Potently inhibits platelet aggregation in vitro (IC 50 = 27-35 nM).

Biochem/physiol Actions

BMY 45778 is a non-prostanoid prostacyclin agonist.

References

[1]. seiler sm, brassard cl, federici me, et al. [3-[4-(4,5-diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (bmy 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, camp levels, protein kinase, and iloprost binding. prostaglandins, 1997, 53(1): 21-35.
[2]. wise h, qian ym, jones rl. a study of prostacyclin mimetics distinguishes neuronal from neutrophil ip receptors. eur j pharmacol, 1995, 278(3): 265-269.

BMY 45778 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMY 45778 Suppliers

China 22 Germany 2 United Kingdom 1 United States 6 Global 31

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152575-66-1, BMY 45778Related Search:

2-METHYL-4,5-DIPHENYLOXAZOLE 5-(4-METHOXYPHENYL)OXAZOLE BMY 45778

[3-(4,5-DIPHENYL[2,4'-BIOXAZOL]-5'-YL)PHENOXY]ACETIC ACID

BMY 45778

Acetic acid, 2-[3-(4,5-diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]-

BMY 45778 >=98% (HPLC)

152575-66-1