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BMY 45778

Product Name
BMY 45778
CAS No.
152575-66-1
Chemical Name
BMY 45778
Synonyms
BMY 45778;BMY 45778 >=98% (HPLC);[3-(4,5-DIPHENYL[2,4'-BIOXAZOL]-5'-YL)PHENOXY]ACETIC ACID;Acetic acid, 2-[3-(4,5-diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]-
CBNumber
CB6723653
Molecular Formula
C26H18N2O5
Formula Weight
438.43
MOL File
152575-66-1.mol
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BMY 45778 Property

Boiling point:
659.9±65.0 °C(Predicted)
Density 
1.298±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
≥67.6 mg/mL in DMSO
form 
powder
pka
3.10±0.10(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BM0032
Product name
BMY 45778
Purity
≥98% (HPLC)
Packaging
25mg
Price
$402
Updated
2022/05/15
Tocris
Product number
1442
Product name
BMY 45778
Purity
≥99%(HPLC)
Packaging
50
Price
$587
Updated
2021/12/16
TRC
Product number
B596418
Product name
BMY 45778
Packaging
2.5mg
Price
$175
Updated
2021/12/16
ApexBio Technology
Product number
B6741
Product name
BMY 45778
Packaging
10mg
Price
$213
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
KIN0008616
Product name
BMY 45778
Purity
95.00%
Packaging
10MG
Price
$709.46
Updated
2021/12/16
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BMY 45778 Chemical Properties,Usage,Production

Uses

BMY 45778 is an agonist for IP receptor to up-regulate the expression of C?/EBPβ and C?/EBPδ.

Definition

ChEBI: BMY 45778 is a bisoxazole. It has a role as a partial prostacyclin agonist.

Biological Activity

Non-prostanoid prostacyclin mimetic that acts as a partial agonist at IP 1 prostacyclin receptors. Potently inhibits platelet aggregation in vitro (IC 50 = 27-35 nM).

Biochem/physiol Actions

BMY 45778 is a non-prostanoid prostacyclin agonist.

References

[1]. seiler sm, brassard cl, federici me, et al. [3-[4-(4,5-diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (bmy 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, camp levels, protein kinase, and iloprost binding. prostaglandins, 1997, 53(1): 21-35.
[2]. wise h, qian ym, jones rl. a study of prostacyclin mimetics distinguishes neuronal from neutrophil ip receptors. eur j pharmacol, 1995, 278(3): 265-269.

BMY 45778 Preparation Products And Raw materials

Raw materials

Preparation Products

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BMY 45778 Suppliers

China 22 Germany 2 United Kingdom 1 United States 6 Global 31
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
BIOTREND Chemicals AG
Tel
--
Fax
--
Email
info@biotrend.ch
Country
Germany
ProdList
1250
Advantage
62

152575-66-1, BMY 45778Related Search:

2-METHYL-4,5-DIPHENYLOXAZOLE 5-(4-METHOXYPHENYL)OXAZOLE BMY 45778

  • [3-(4,5-DIPHENYL[2,4'-BIOXAZOL]-5'-YL)PHENOXY]ACETIC ACID
  • BMY 45778
  • Acetic acid, 2-[3-(4,5-diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]-
  • BMY 45778 >=98% (HPLC)
  • 152575-66-1