Bosutinib Impurity 2 (N-Desmethyl Bosutinib)

Product Name
Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
CAS No.
380843-81-2
Chemical Name
Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
Synonyms
Desmethyl Bosutinib;Bosutinib Impurity 2 (N-Desmethyl Bosutinib);3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-
CBNumber
CB67247990
Molecular Formula
C25H27Cl2N5O3
Formula Weight
516.42
MOL File
380843-81-2.mol
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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Property

Melting point:
123-125 °C
Boiling point:
655.4±55.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
pka
9.19±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D435305
Product name
4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Packaging
10mg
Price
$165
Updated
2021/12/16
TRC
Product number
D435305
Product name
4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Packaging
25mg
Price
$365
Updated
2021/12/16
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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Chemical Properties,Usage,Production

Uses

Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors.

Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Preparation Products And Raw materials

Raw materials

Preparation Products

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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) Suppliers

Amatek Scientific Co. Ltd.
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Shenzhen ruikai de biotechnology co., ltd.
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Nanjing Shizhou Biology Technology Co.,Ltd
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Energy Chemical
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380843-81-2, Bosutinib Impurity 2 (N-Desmethyl Bosutinib)Related Search:


  • Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
  • Desmethyl Bosutinib
  • 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-
  • 380843-81-2