4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE

Product Name: 4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE
CAS No.: 607737-87-1
Chemical Name: 4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE
Synonyms: A77-01;A-77-01;A 77-01;CS-1775;A7701;A 7701; A-7701;A 77-01, 10 mM in DMSO;4-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoline;4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE;4-[5-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]quinoline;Quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-
CBNumber: CB6727914
Molecular Formula: C18H14N4
Formula Weight: 286.33
MOL File: 607737-87-1.mol

More

Less

4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE Property

storage temp.: Store at -20°C
solubility: insoluble in H2O; ≥14.3 mg/mL in DMSO; ≥8.84 mg/mL in EtOH with gentle warming and ultrasonic
form: solid
color: Off-white to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 18396
Product name: A-77-01
Purity: ≥98%
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 18396
Product name: A-77-01
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 18396
Product name: A-77-01
Purity: ≥98%
Packaging: 10mg
Price: $236
Updated: 2024/03/01

Cayman Chemical

Product number: 18396
Product name: A-77-01
Purity: ≥98%
Packaging: 25mg
Price: $492
Updated: 2024/03/01

Tocris

Product number: 6712
Product name: A77-01
Purity: ≥98%(HPLC)
Packaging: 25
Price: $577
Updated: 2021/12/16

More

Less

4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE Chemical Properties,Usage,Production

Uses

A 77-01 is a potent inhibitor of transforming growth factor (TGF)-β type I receptor superfamily activin-like kinase ALK5 with an IC50 of 25 nM[1].

storage

Store at +4°C

References

[1] Tojo M, et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 2005 Nov;96(11):791-800. DOI:10.1111/j.1349-7006.2005.00103.x

4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE Suppliers

China 57 The Netherlands 1 United Kingdom 1 United States 17 Global 76

Axon Medchem BV

Tel: --
Fax: --
Email: info@axonmedchem.com
Country: The Netherlands
ProdList: 477
Advantage: 30

607737-87-1, 4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINERelated Search:

LY-364947 A-83-01 4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE

4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE

A 77-01

A-77-01

A77-01

4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]quinoline A 77-01

4-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoline

CS-1775

4-[5-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]quinoline

A7701;A 7701; A-7701

Quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-

TGF-β Receptor,Transforming growth factor beta receptors,A 77-01,Inhibitor,A 77 01,inhibit,A 7701

A 77-01, 10 mM in DMSO

607737-87-1

Inhibitors