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3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE

Product Name
3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE
CAS No.
86-08-8
Chemical Name
3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE
Synonyms
APAD;NSC 20275;3-ACETYLPYRIDINE NAD;3-Acetylpyridine adenine;acetylpyridineadeninedinucleotide;acetyldiphosphopyridine nucleotide;3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE;3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, REDUCED FORM;3-Acetylpyridine adenine dinucleotide, oxidised form;3-Acetylpyridine hypoxanthine dinucleotide,oxidized form
CBNumber
CB6733207
Molecular Formula
C22H28N6O14P2
Formula Weight
662.44
MOL File
86-08-8.mol
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3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE Property

storage temp. 
−20°C
solubility 
PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
color 
White to light yellow
biological source
Porcine brain
Water Solubility 
water: 50mg/mL, clear, colorless to faintly yellow
InChIKey
KPVQNXLUPNWQHM-MFRNWTRNNA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=O)C)=C3)O2)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,15,16,17,19,32,r|
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A5251
Product name
3-Acetylpyridine adenine dinucleotide
Purity
≥85%
Packaging
25 mg
Price
$175
Updated
2025/07/31
Sigma-Aldrich
Product number
A5251
Product name
3-Acetylpyridine adenine dinucleotide
Purity
≥85%
Packaging
100 mg
Price
$561
Updated
2025/07/31
Sigma-Aldrich
Product number
A5251
Product name
3-Acetylpyridine adenine dinucleotide
Purity
≥85%
Packaging
500 mg
Price
$2010
Updated
2025/07/31
Sigma-Aldrich
Product number
A5251
Product name
3-Acetylpyridine adenine dinucleotide
Purity
≥85%
Packaging
1 g
Price
$3170
Updated
2025/07/31
Cayman Chemical
Product number
21884
Product name
3-Acetylpyridine NAD
Purity
≥95%
Packaging
25mg
Price
$93
Updated
2024/03/01
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3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE Chemical Properties,Usage,Production

Description

3-Acetylpyridine NAD (APAD) is an analog of NAD+ (free acid) (nicotinamide adenine dinucleotide; ), a signaling molecule and cofactor or substrate for many enzymes. APAD has been used to study the mechanisms of oxidative phosphorylation. It can be reduced by transdehydrogenase from NADH (sodium salt) . It can be reduced more efficiently and is more stable than NAD+; thus, it is useful as a substitute.

Uses

3-Acetylpyridine adenine dinucleotide, 90% is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 90% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite[1][2].

Definition

ChEBI: 3-acetylpyridine adenine dinucleotide is an organic molecular entity.

References

[1] Boland MJ. NADH-dependent glutamate synthase from lupin nodules. Reactions with oxidised and reduced 3-acetylpyridine-adenine dinucleotide. Eur J Biochem. 1981 Apr;115(3):485-9. PMID:7238515
[2] Ciaccio EI. The inhibition of lactate dehydrogenase by 3-acetylpyridine adenine dinucleotide and bisulfite. J Biol Chem. 1966 Apr 10;241(7):1581-6. PMID:5946616

3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91

86-08-8, 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDERelated Search:


  • acetyldiphosphopyridine nucleotide
  • 3-Acetylpyridine adenine dinucleotide, oxidised form 92+%
  • 5'-ester with 3-acetyl-1-b-D-ribofuranosylpyridinium, inner salt
  • APAD
  • 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE
  • 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, REDUCED FORM
  • 3-ACETYLPYRIDINE NAD
  • 3-Acetylpyridine hypoxanthine dinucleotide,oxidized form
  • 3-Acetyl-1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyridin-1-ium
  • acetylpyridineadeninedinucleotide
  • NSC 20275
  • 3-Acetylpyridine adenine
  • 3-Acetylpyridine adenine dinucleotide, oxidised form
  • 86-08-8
  • C22H28N6O14P2
  • Biochemicals and Reagents
  • BioChemical
  • Nucleosides, Nucleotides, Oligonucleotides
  • Oligonucleotides, DNA, and RNA
  • nucleoside
  • Other