5-BENZYLOXY-1H-INDAZOLE
- Product Name
- 5-BENZYLOXY-1H-INDAZOLE
- CAS No.
- 78299-75-9
- Chemical Name
- 5-BENZYLOXY-1H-INDAZOLE
- Synonyms
- oxy)-1H-indazoL;5-(Benzyloxy)indazole;5-BENZYLOXY-1H-INDAZOLE;5-(Phenylmethoxy)-1H-indazole;1H-Indazole, 5-(phenylmethoxy)-
- CBNumber
- CB6745552
- Molecular Formula
- C14H12N2O
- Formula Weight
- 224.26
- MOL File
- 78299-75-9.mol
5-BENZYLOXY-1H-INDAZOLE Property
- Boiling point:
- 422.4±20.0 °C(Predicted)
- Density
- 1.247±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.52±0.40(Predicted)
- Appearance
- Yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B593883
- Product name
- 5-Benzyloxy-1H-indazole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB52069
- Product name
- 5-Benzyloxy-1H-indazole
- Packaging
- 50mg
- Price
- $81
- Updated
- 2021/12/16
- Product number
- FB52069
- Product name
- 5-Benzyloxy-1H-indazole
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FB52069
- Product name
- 5-Benzyloxy-1H-indazole
- Packaging
- 250mg
- Price
- $162.5
- Updated
- 2021/12/16
- Product number
- Y4086
- Product name
- 5-(Benzyloxy)-1H-indazole
- Packaging
- 1g
- Price
- $224
- Updated
- 2021/12/16
5-BENZYLOXY-1H-INDAZOLE Chemical Properties,Usage,Production
Synthesis
15579-15-4
100-39-0
78299-75-9
General procedure for the synthesis of 5-(benzyloxy)-1H-indazole from 1H-indazol-5-ol and benzyl bromide: Benzyl bromide (0.089 mL, 0.745 mmol) and potassium carbonate (103 mg, 0.745 mmol) were sequentially added to a N,N-dimethylformamide (2 mL) containing 1H-indazol-5-ol (100 mg, 0.745 mmol) ) solution. The reaction mixture was heated to 40 °C and maintained at this temperature for 2 hours. Upon completion of the reaction, the mixture was poured into water (20 mL) and extracted with ethyl acetate (20 mL x 2). The organic layers were combined and dried with anhydrous magnesium sulfate. The dried organic layer was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford the target product 5-(benzyloxy)-1H-indazole (63 mg, 38% yield). The melting point of the product was 179-181 °C.
References
[1] Patent: WO2011/123937, 2011, A1. Location in patent: Page/Page column 152-153
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 17, p. 4968 - 4997
[3] Patent: EP1403255, 2004, A1. Location in patent: Page 97
5-BENZYLOXY-1H-INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BENZYLOXY-1H-INDAZOLE manufacturers
- Product
- 5-BENZYLOXY-1H-INDAZOLE 78299-75-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-25