ChemicalBook > CAS DataBase List > 5-BENZYLOXY-1H-INDAZOLE

5-BENZYLOXY-1H-INDAZOLE

Product Name
5-BENZYLOXY-1H-INDAZOLE
CAS No.
78299-75-9
Chemical Name
5-BENZYLOXY-1H-INDAZOLE
Synonyms
oxy)-1H-indazoL;5-(Benzyloxy)indazole;5-BENZYLOXY-1H-INDAZOLE;5-(Phenylmethoxy)-1H-indazole;1H-Indazole, 5-(phenylmethoxy)-
CBNumber
CB6745552
Molecular Formula
C14H12N2O
Formula Weight
224.26
MOL File
78299-75-9.mol
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5-BENZYLOXY-1H-INDAZOLE Property

Boiling point:
422.4±20.0 °C(Predicted)
Density 
1.247±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
13.52±0.40(Predicted)
Appearance
Yellow to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B593883
Product name
5-Benzyloxy-1H-indazole
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB52069
Product name
5-Benzyloxy-1H-indazole
Packaging
50mg
Price
$81
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB52069
Product name
5-Benzyloxy-1H-indazole
Packaging
100mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB52069
Product name
5-Benzyloxy-1H-indazole
Packaging
250mg
Price
$162.5
Updated
2021/12/16
AK Scientific
Product number
Y4086
Product name
5-(Benzyloxy)-1H-indazole
Packaging
1g
Price
$224
Updated
2021/12/16
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5-BENZYLOXY-1H-INDAZOLE Chemical Properties,Usage,Production

Synthesis

15579-15-4

100-39-0

78299-75-9

General procedure for the synthesis of 5-(benzyloxy)-1H-indazole from 1H-indazol-5-ol and benzyl bromide: Benzyl bromide (0.089 mL, 0.745 mmol) and potassium carbonate (103 mg, 0.745 mmol) were sequentially added to a N,N-dimethylformamide (2 mL) containing 1H-indazol-5-ol (100 mg, 0.745 mmol) ) solution. The reaction mixture was heated to 40 °C and maintained at this temperature for 2 hours. Upon completion of the reaction, the mixture was poured into water (20 mL) and extracted with ethyl acetate (20 mL x 2). The organic layers were combined and dried with anhydrous magnesium sulfate. The dried organic layer was concentrated under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate) to afford the target product 5-(benzyloxy)-1H-indazole (63 mg, 38% yield). The melting point of the product was 179-181 °C.

References

[1] Patent: WO2011/123937, 2011, A1. Location in patent: Page/Page column 152-153
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 17, p. 4968 - 4997
[3] Patent: EP1403255, 2004, A1. Location in patent: Page 97

5-BENZYLOXY-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BENZYLOXY-1H-INDAZOLE Suppliers

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View Lastest Price from 5-BENZYLOXY-1H-INDAZOLE manufacturers

Career Henan Chemical Co
Product
5-BENZYLOXY-1H-INDAZOLE 78299-75-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-25

78299-75-9, 5-BENZYLOXY-1H-INDAZOLERelated Search:


  • 5-BENZYLOXY-1H-INDAZOLE
  • 1H-Indazole, 5-(phenylmethoxy)-
  • 5-(Benzyloxy)indazole
  • 5-(Phenylmethoxy)-1H-indazole
  • oxy)-1H-indazoL
  • 78299-75-9
  • pharmacetical