2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE
- Product Name
- 2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE
- CAS No.
- 1007-99-4
- Chemical Name
- 2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE
- Synonyms
- 2-Amino-6-chloro-5-nitropyrimidin-4-ol;ACHNP;AKOS 92816;2-Amino-6-chloro-5-nitro-4(3H)-pyrimidone;2-amino-6-chloro-5-nitro-1H-pyrimidin-4-one;2-Amino-6-chloro-5-nitropyrimidin-4(5H)-one;2-Amino-6-chloro-5-nitro-4(1H)-pyrimidinone;2-azanyl-6-chloro-5-nitro-1H-pyrimidin-4-one;4(1H)-Pyrimidinone,2-amino-6-chloro-5-nitro-;2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE
- CBNumber
- CB6747046
- Molecular Formula
- C4H3ClN4O3
- Formula Weight
- 190.54
- MOL File
- 1007-99-4.mol
2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE Property
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Boiling point:
- 268.2±50.0 °C(Predicted)
- Density
- 2.20±0.1 g/cm3(Predicted)
- Melting point:
- >350 °C
- pka
- 4≅+-.0.50(Predicted)
- CAS DataBase Reference
- 1007-99-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A604163
- Product name
- 2-Amino-4-chloro-6-hydroxy-5-nitropyrimidine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W000783
- Product name
- 2-amino-6-chloro-5-nitropyrimidin-4-ol
- Packaging
- 100mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- FA12037
- Product name
- 2-Amino-4-chloro-5-nitro-6-hydroxypyrimidine
- Packaging
- 5G
- Price
- $650
- Updated
- 2021/12/16
- Product number
- 094520
- Product name
- 2-Amino-4-chloro-6-hydroxy-5-nitropyrimidine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $680
- Updated
- 2021/12/16
- Product number
- FA12037
- Product name
- 2-Amino-4-chloro-5-nitro-6-hydroxypyrimidine
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE Chemical Properties,Usage,Production
Synthesis
1194-21-4
1007-99-4
General procedure for the synthesis of 2-amino-4-chloro-5-nitro-6-hydroxypyrimidines from 2-amino-6-chloro-4-hydroxypyrimidines: 2-amino-6-chloropyrimidin-4(3H)-one (10 g, 68.73 mmol) was dissolved in 98% sulfuric acid (46 mL) at 40 °C, keeping stirring. Subsequently, 65% nitric acid (9 g) was slowly added dropwise to the above solution. The reaction mixture was continued to be stirred at room temperature for 1 hour. Upon completion of the reaction, the solution was carefully poured into 100 g of ice to quench the reaction. The precipitate was collected by filtration and the resulting filter cake was dried in a reduced pressure oven to afford 12 g (87% yield) of the target product 2-amino-6-chloro-5-nitropyrimidin-4(3H)-one as a yellow solid. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 7.13 (1H, s), 8.59 (1H, s), 12.16 (1H, s).
References
[1] Chemistry (Weinheim an der Bergstrasse, Germany), 2002, vol. 8, # 1, p. 293 - 301
[2] Patent: US4939252, 1990, A
[3] Patent: WO2009/139834, 2009, A1. Location in patent: Page/Page column 93-94
[4] Journal of Heterocyclic Chemistry, 1985, vol. 22, # 4, p. 1035 - 1040
[5] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985, p. 1645 - 1660
2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE manufacturers
- Product
- 2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE 1007-99-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-09
- Product
- 2-AMINO-4-CHLORO-6-HYDROXY-5-NITROPYRIMIDINE 1007-99-4
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-03-13