1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
- Product Name
- 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
- CAS No.
- 189882-33-5
- Chemical Name
- 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
- Synonyms
- 6-CYANO-7-AZAINDOLE;7-Azaindole-6-carbonitrile;6-Cyano-1H-pyrrolo[2,3-b]pyridine;PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE;1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE;1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI);1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE ISO 9001:2015 REACH
- CBNumber
- CB6748962
- Molecular Formula
- C8H5N3
- Formula Weight
- 143.15
- MOL File
- 189882-33-5.mol
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Property
- Melting point:
- 187.4 °C
- Boiling point:
- 463.9±28.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 6.56±0.40(Predicted)
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B530363
- Product name
- 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- OR961921
- Product name
- 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile
- Purity
- 95%
- Packaging
- 250mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 3H37-1-35
- Product name
- 6-Cyano-7-azaindole
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- W4085
- Product name
- 6-Cyano-7-azaindole
- Packaging
- 250mg
- Price
- $253
- Updated
- 2021/12/16
- Product number
- 3H37-1-35
- Product name
- 6-Cyano-7-azaindole
- Packaging
- 1g
- Price
- $375
- Updated
- 2021/12/16
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Chemical Properties,Usage,Production
Description
7-Azaindole, as a bioisostere of indole or purine, is widely used in drug development. Among them, 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile is a key intermediate for the synthesis of a class of selective cyclin-dependent kinase (CDK) 7 inhibitors. Among mammalian CDKs, CDK7 has a unique integrated kinase activity that helps regulate the cell cycle and gene transcription. 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile can be prepared using 7-azaindole-7-oxide as a raw material.
Chemical Properties
Class white powder
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile manufacturers
- Product
- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE 189882-33-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-28
- Product
- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE 189882-33-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-11