ChemicalBook > CAS DataBase List > 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile

1H-pyrrolo[2,3-b]pyridine-6-carbonitrile

Product Name
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
CAS No.
189882-33-5
Chemical Name
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
Synonyms
6-CYANO-7-AZAINDOLE;7-Azaindole-6-carbonitrile;6-Cyano-1H-pyrrolo[2,3-b]pyridine;PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE;1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE;1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI);1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE ISO 9001：2015 REACH
CBNumber
CB6748962
Molecular Formula
C8H5N3
Formula Weight
143.15
MOL File
189882-33-5.mol
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1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Property

Melting point:
187.4 °C
Boiling point:
463.9±28.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
6.56±0.40(Predicted)
Appearance
Light yellow to brown Solid
InChI
InChI=1S/C8H5N3/c9-5-7-2-1-6-3-4-10-8(6)11-7/h1-4H,(H,10,11)
InChIKey
GAFBPZMOMITHLG-UHFFFAOYSA-N
SMILES
C12NC=CC1=CC=C(C#N)N=2
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B530363
Product name
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
Packaging
100mg
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
OR961921
Product name
1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile
Purity
95%
Packaging
250mg
Price
$200
Updated
2021/12/16
SynQuest Laboratories
Product number
3H37-1-35
Product name
6-Cyano-7-azaindole
Packaging
250mg
Price
$125
Updated
2021/12/16
AK Scientific
Product number
W4085
Product name
6-Cyano-7-azaindole
Packaging
250mg
Price
$253
Updated
2021/12/16
SynQuest Laboratories
Product number
3H37-1-35
Product name
6-Cyano-7-azaindole
Packaging
1g
Price
$375
Updated
2021/12/16
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1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Chemical Properties,Usage,Production

Description

7-Azaindole, as a bioisostere of indole or purine, is widely used in drug development. Among them, 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile is a key intermediate for the synthesis of a class of selective cyclin-dependent kinase (CDK) 7 inhibitors. Among mammalian CDKs, CDK7 has a unique integrated kinase activity that helps regulate the cell cycle and gene transcription. 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile can be prepared using 7-azaindole-7-oxide as a raw material.

Chemical Properties

Class white powder

1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Suppliers

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View Lastest Price from 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile manufacturers

Dideu Industries Group Limited
Product
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE 189882-33-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-28
Career Henan Chemical Co
Product
1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE 189882-33-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-11

189882-33-5, 1H-pyrrolo[2,3-b]pyridine-6-carbonitrileRelated Search:

6-NITRO-1H-PYRROLO[2,3-B]PYRIDINE 4-METHYL-7-AZAINDOLE 1,7-DIDEAZAADENINE 4-FLUORO-7-AZAINDOLE 1H-Pyrrolo[2,3-b]pyridine, 6-fluoro- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE 6-METHYL-1H-PYRROLO[2,3-B]PYRIDINE

  • 7-Azaindole-6-carbonitrile
  • 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
  • 6-Cyano-1H-pyrrolo[2,3-b]pyridine
  • 6-CYANO-7-AZAINDOLE
  • 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI)
  • PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
  • 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE ISO 9001：2015 REACH
  • 189882-33-5
  • Azaindoles
  • PYRIDINE