Ethynodiol diacetate

Product Name: Ethynodiol diacetate
CAS No.: 297-76-7
Chemical Name: Ethynodiol diacetate
Synonyms: Femulen;CB-8080;ovulen50;SC 11800;8080c.b.;Etynodiol;Luteonorm;Metrodiol;Ovulen 50;Continuin
CBNumber: CB6749404
Molecular Formula: C24H32O4
Formula Weight: 384.51
MOL File: 297-76-7.mol

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Ethynodiol diacetate Property

Melting point:: ~126-127°
alpha: D -72.5° (chloroform)
Boiling point:: 431.17°C (rough estimate)
Density: 1.0474 (rough estimate)
refractive index: 1.4860 (estimate)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Solid
color: White
Water Solubility: 1.4mg/L(25 ºC)
CAS DataBase Reference: 297-76-7(CAS DataBase Reference)
NIST Chemistry Reference: Ethynodiol diacetate(297-76-7)
EPA Substance Registry System: Ethynodiol diacetate (297-76-7)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-40
Safety Statements: 22-36
WGK Germany: 3
RTECS: RC8963000
HS Code: 2937230000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E7263
Product name: Ethynodiol diacetate
Packaging: 500mg
Price: $100
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1268003
Product name: Ethynodiol diacetate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $393
Updated: 2024/03/01

TCI Chemical

Product number: E1315
Product name: Ethynodiol Diacetate
Packaging: 1G
Price: $120
Updated: 2024/03/01

TCI Chemical

Product number: E1315
Product name: Ethynodiol Diacetate
Packaging: 5G
Price: $413
Updated: 2024/03/01

Cayman Chemical

Product number: 29854
Product name: Ethynodiol Diacetate
Packaging: 500mg
Price: $81
Updated: 2024/03/01

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Ethynodiol diacetate Chemical Properties,Usage,Production

Description

Ethynodiol diacetate is a synthetic progestogen. It prevents the development of osteoporosis in ovariectomized rats when administered at a dose of 9 μg/animal per day. Ethynodiol diacetate inhibits copulatory ovulation in rabbits. Formulations containing ethynodiol diacetate have been used as oral contraceptives.

Originator

Lutometrodiol,Searle,France,1965

Uses

anticonvulsant

Uses

Ethynodiol Diacetate is used as a hormonal contraceptive, birth control.

Definition

ChEBI: Ethynodiol diacetate is a steroid ester and a terminal acetylenic compound. It has a role as an estrogen receptor modulator, a contraceptive drug and a synthetic oral contraceptive. It is functionally related to an ethynodiol.

Manufacturing Process

A mixture of 30 parts of 17α-ethynyl-19-norandrost-4-ene-3β,17β-diol, 360 parts of dry pyridine, and 111 parts of acetic anhydride, under nitrogen, is stirred and heated at the reflux temperature for about 5 hours. This reaction mixture is cooled, then poured into approximately 3,500 parts of cold water and the resulting aqueous mixture is stirred at room temperature for about 0.5 hour. The precipitate which forms is collected by filtration, then is washed on the filter with water and dried in air. This solid material is extracted into ether, and the ether solution is washed successively with 10% aqueous

Therapeutic Function

Progestin; Oral contraceptive ingredient

General Description

Ethynodiol diacetate, 19-norpregn-4-en-20-yne-3β,17α-diol diacetate, is a prodrug ofnorethindrone. A combination of hydrolysis of both estersand oxidation of the C3 alcohol to the ketone is necessary toprovide the fully active progestin.

Safety Profile

Suspected carcinogen. Human reproductive effects by ingestion: menstrual cycle changes. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.

Ethynodiol diacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethynodiol diacetate Suppliers

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View Lastest Price from Ethynodiol diacetate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Ethynodiol diacetate 297-76-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000
Release date: 2023-07-27

Hebei Mojin Biotechnology Co., Ltd

Product: Ethynodiol diacetate 297-76-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-10-11

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Product: Ethynodiol diacetate 297-76-7
Price: US $0.00/KG
Min. Order: 100g
Purity: 98%+
Supply Ability: 100kg
Release date: 2020-10-12

297-76-7, Ethynodiol diacetateRelated Search:

Levonorgestrel Pancuronium bromide Norethindrone Lynestrenol (S)-1-OCTYN-3-OL 4-METHYL-1-PENTYN-3-OL PROPARGYL ACETATE 10-UNDECYN-1-OL 3,4-DIMETHYL-1-PENTYN-3-OL 19-Norandrostenediol 3,5-DIMETHYL-1-HEXYN-3-OL 3-CYCLOHEXYL-1-PROPYNE 3-METHYL-1-DODECYN-3-OL 1-HEXADECYNE 3-METHYL-1-NONYN-3-OL 1-PENTADECYNE NOR-1 3-METHYL-1-OCTYN-3-OL

(3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol diacetate

(3-beta,17-alpha)-19-norpregn-4-en-20-yne-3,17-dioldiacetate

17-(Acetyloxy)-17-ethynylestr-4-en-3-yl acetate

17-alpha-Ethynyl-19-norandrost-4-ene-3-beta,17-beta-diol diacetate

17-alpha-ethynyl-19-norandrost-4-ene-3-beta,17-beta-dioldiacetate

17-alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate

17-alpha-ethynyl-3,17-dihydroxy-4-estrenediacetate

17-alpha-Ethynyl-4-estrene-3-beta,17-beta-diol diacetate

17-alpha-ethynyl-4-estrene-3-beta,17-beta-dioldiacetate

17-alpha-Ethynyl-4-estrene-3-beta,17-diol diacetate

17-alpha-ethynyl-4-estrene-3-beta,17-dioldiacetate

17-alpha-Ethynylestr-4-ene-3-beta,17-beta-diol acetate

acetic acid [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester

component of Demulen

component of Demulon

component of Luteolas

component of Metrulen

component of Miniluteolas

component of Ovaras

Ethinodiol diacetate

ethinodioldiacetate

Ethynodiol

ethynodiolacetate

Etynodiol

Femulen

Luteonorm

Luto-metrodiol

Metrodiol

Metrodiol diacetate

metrodioldiacetate

Ovulen 50

ovulen50

SC 11800

3BETA,17BETA-DIACETOXY-17ALPHA-ETHYNYL-4-ESTRENE

ETHYNODIOL DIACETATE

19-nor-17a-pregn-4-en-20-yne-3b,17-diol diacetate

17alpha-ethynyl-4-estrene-3b,17b-diol-3,17-diacetate

8080c.b.

beta-Ethynodiol diacetate

beta-ethynodioldiacetate

Cervicundin

component of Conova

4-ESTREN-17-ALPHA-ETHYNYL-3-BETA, 17-BETA-DIOL DIACETATE

17-alpha-ethynylestr-4-ene-3-beta,17-beta-diolacetate

19-Nor-17alpha-pregn-4-en-20-yn-3beta,17-diol diacetate

19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol diacetate

19-nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol,diacetate

19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3beta,17alpha)-

3-beta, 17-beta-Diacetoxy-17-alpha-ethynyl-4-oestrene

3-beta,17-beta-diacetoxy-17-alpha-ethynyl-4-oestrene

3-beta,17-beta-Diacetoxy-19-nor-17-alpha-pregn-4-en-20-yne

8080 C. B.

17a-Ethynyl-4-estren-3b,17-diol diacetate

19-Norpregn-4-en-20-yne-3,17-diol, 3,17-diacetate, (3β,17α)-

(3β, 17α)-19-Norpregn-4-en-20-yne-3,17-diol diacetate

Etynodiol acetate

Double vinegar ethynodiol

etynodiol di(acetate)