ANTI-CASPASE-3
- Product Name
- ANTI-CASPASE-3
- Chemical Name
- ANTI-CASPASE-3
- Synonyms
- ANTI-LICE;ANTI-YAMA;Anti-SCA1;ANTI-CASP3;ANTI-CPP32;ANTI-ICE-3;Anti-CPP32B;ANTI-APOPAIN;ANTI-CASPASE-3;ANTI-CPP32: HRPO
- CBNumber
- CB6750242
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-CASPASE-3 Property
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- rabbit
Safety
- WGK Germany
- 3
- Storage Class
- 12 - Non Combustible Liquids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H312Harmful in contact with skin
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SAB5701085
- Product name
- Anti- Caspase-3 antibody produced in rabbit
- Packaging
- 100 μL
- Price
- $418
- Updated
- 2025/07/31
- Product number
- SAB5700914
- Product name
- Anti- Caspase-3 antibody produced in rabbit
- Packaging
- 100 μL
- Price
- $418
- Updated
- 2025/07/31
- Product number
- SAB5700708
- Product name
- Anti-CASP3 antibody produced in rabbit
- Packaging
- 100 μL
- Price
- $418
- Updated
- 2025/07/31
- Product number
- SAB5700196
- Product name
- Anti-Caspase 3 antibody produced in rabbit
- Packaging
- 100 μL
- Price
- $418
- Updated
- 2025/07/31
- Product number
- SAB4503291
- Product name
- Anti-CASP3 antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μg
- Price
- $522
- Updated
- 2025/07/31
ANTI-CASPASE-3 Chemical Properties,Usage,Production
Uses
Anti-Caspase 3, Active antibody has been used:
- for western blotting of cytochrome c for caspase activation
- as primary antibody in immunofluorescence staining of embryos and postnatal mice cryosections
- in Western blot analysis of activated caspase 3
- as a primary antibody in immunodetection of rat brain sections
General Description
Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3is mapped to human chromosome 4q35.1.
Biochem/physiol Actions
Caspase 3 is one of the key effectors of apoptosis. It acts downstream of caspase 9 in the apoptotic pathway. During apoptosis, it gets activated by proteolytic cleavage into the 17-19 kDa (p17, p18) and 12 kDa (p12) active subunits. Any alteraion in CASP-3 in mice, causes premature lethality. It has also shown that the deletion of gene affects brain development resulting of hyperplasias and disorganized cell deployement. Clinically it is related to Huntington disease (HD). Caspase 3 brings about cell death by activating CAD (caspase activated DNAse I), an endonuclease that causes degradation of chromosomal DNA.
ANTI-CASPASE-3 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CASPASE-3 Suppliers
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- 021-61415566 800-8193336
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