ChemicalBook > CAS DataBase List > METHYL 2-METHOXY-6-METHYLBENZOATE

METHYL 2-METHOXY-6-METHYLBENZOATE

Product Name
METHYL 2-METHOXY-6-METHYLBENZOATE
CAS No.
79383-44-1
Chemical Name
METHYL 2-METHOXY-6-METHYLBENZOATE
Synonyms
METHYL 2-METHOXY-6-METHYLBENZOATE;2-Methoxy-6-Methyl-benzoic acid Methyl ester;Benzoic acid, 2-Methoxy-6-Methyl-, Methyl ester
CBNumber
CB6751007
Molecular Formula
C10H12O3
Formula Weight
180.2
MOL File
79383-44-1.mol
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METHYL 2-METHOXY-6-METHYLBENZOATE Property

Boiling point:
95-96 °C(Press: 0.5 Torr)
Density 
1.075±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Appearance
Light yellow to yellow Liquid
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M356755
Product name
methyl2-methoxy-6-methylbenzoate
Packaging
500mg
Price
$200
Updated
2021/12/16
Matrix Scientific
Product number
077350
Product name
Methyl 2-methoxy-6-methylbenzoate
Packaging
500mg
Price
$252
Updated
2021/12/16
AK Scientific
Product number
J57236
Product name
Methyl2-methoxy-6-methylbenzoate
Packaging
1g
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
077350
Product name
Methyl 2-methoxy-6-methylbenzoate
Packaging
1g
Price
$315
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0379509
Product name
METHYL-2-METHOXY-6-METHYLBENZOATE
Purity
95.00%
Packaging
5MG
Price
$497.45
Updated
2021/12/16
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METHYL 2-METHOXY-6-METHYLBENZOATE Chemical Properties,Usage,Production

Synthesis

6161-65-5

74-88-4

79383-44-1

General procedure for the synthesis of methyl 2-methoxy-6-methylbenzoate from 2-methoxy-6-methylbenzoic acid and iodomethane: To a solution of 2-methoxy-6-methylbenzoic acid (1.0 eq.) in N,N-dimethylformamide (DMF, 3.8 mL/mmol 2-methoxy-6-methylbenzoic acid) was added iodomethane (3.0-6.0 eq.) and potassium carbonate ( K2CO3, 2.5-5.0 eq.). The reaction mixture was heated to 70 °C and stirred for 17-18 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by addition of water (H2O). The organic phase was extracted with ethyl acetate (EtOAc), the organic layers were combined, dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure in a fume hood to give the target product methyl 2-methoxy-6-methylbenzoate. Precautions: Iodomethane is toxic and carcinogenic, the operation should wear gloves and be carried out in a well-ventilated fume hood.

References

[1] Tetrahedron, 2018, vol. 74, # 2, p. 224 - 239
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 1, p. 360 - 365

METHYL 2-METHOXY-6-METHYLBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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