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L-Sulforaphane

Product Name
L-Sulforaphane
CAS No.
142825-10-3
Chemical Name
L-Sulforaphane
Synonyms
NSC47734;NSC 47734;NSC-47734;sulphorane;L-SULFORAPHAN;S-SULFORAPHANE;R-SULFORAPHANE;D-SULFORAPHANE;L-SULFORAPHANE;R,S-SULFORAPHANE
CBNumber
CB6765543
Molecular Formula
C6H11NOS2
Formula Weight
177.29
MOL File
142825-10-3.mol
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L-Sulforaphane Property

Boiling point:
368.2±25.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: 40 mg/mL, soluble
form 
liquid
color 
slightly yellow
InChIKey
SUVMJBTUFCVSAD-UHFFFAOYSA-N
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Safety

Safety Statements 
23-24/25-22
WGK Germany 
3
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S6317
Product name
L-Sulforaphane
Purity
≥95% (HPLC), oil
Packaging
5mg
Price
$279
Updated
2024/03/01
Cayman Chemical
Product number
14797
Product name
L-Sulforaphane
Purity
≥98%
Packaging
1mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
14797
Product name
L-Sulforaphane
Purity
≥98%
Packaging
5mg
Price
$111
Updated
2024/03/01
Cayman Chemical
Product number
14797
Product name
L-Sulforaphane
Purity
≥98%
Packaging
10mg
Price
$177
Updated
2024/03/01
Cayman Chemical
Product number
14797
Product name
L-Sulforaphane
Purity
≥98%
Packaging
50mg
Price
$698
Updated
2024/03/01
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L-Sulforaphane Chemical Properties,Usage,Production

Description

Sulforaphane is a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale.

Chemical Properties

L-Sulforaphane is a clear Pale Yellow Oil and It is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli. soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

L-sulforaphane is an Antitumor agent and has antioxidant, anti-cancer, anti-ultraviolet, help clear lung bacteria, and prevent gout. It was found to inhibit chemically induced mammary tumor formation in rats. L-Sulforaphane has been reported to prevent NFκB binding, which results in downregulation of apoptosis inhibitors therefore inducing apoptosis. It also displays a capacity to inhibit intracellular, extracellular, and antibiotic-resistant strains of Helicobacter pylori. Additionally, L-Sulforaphane has been found to prevent clonogenicity. This Sulforaphane is sold in the L-enantiomer form.

Application

L-Sulforaphane was used to study Nrf2-mediated signaling in mouse primary preadipocytes and murine macrophage RAW 264.7 cell line.

Definition

ChEBI: (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.

Biochem/physiol Actions

L-Sulforaphane is a potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.
Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.

L-Sulforaphane Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Sulforaphane Suppliers

Shanghai Mokai Pharmaceutical Technology Co., Ltd.
Tel
021-60951261 18601606476
Email
nancy@mkpharma.cn
Country
China
ProdList
453
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
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View Lastest Price from L-Sulforaphane manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Sulforaphane 142825-10-3
Price
US $0.00/kg
Min. Order
1kg
Purity
1%-10% 98%
Supply Ability
1000 kg
Release date
2024-04-20
Hebei Zhanyao Biotechnology Co. Ltd
Product
Sulforaphane 142825-10-3
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-10-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
(R)-sulforaphane 142825-10-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

142825-10-3, L-SulforaphaneRelated Search:


  • (R)-1-ISOTHIOCYANATO-4-(METHYLSULFINYL)BUTANE
  • R,S-SULFORAPHANE
  • R-SULFORAPHANE
  • S-SULFORAPHANE
  • SULFORAPHANE, L-
  • SULFORAPHANE, D-
  • SULFORAPHANE, DL-
  • 4-METHYLSULPHINYLBUTYLISOTHIOCYANATE
  • L-SULFORAPHAN
  • (R)-1-Isothiocyanato-4-(methylsulfinyl)butane, 4-Methylsulfinylbutyl isothiocyanate
  • R-Sulforaphane (in ethanol)
  • (+)-1-ISOTHIOCYANATE-4R(METHYLSULFINYL)-BUTANE
  • 1-ISOTHIOCYANATO-4-(METHYLSULFIYL)-BUTANE
  • ((-)1-ISOTHIOCYANATO-4R-METHYLSULFINYL)BUTANE
  • (-)1-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-BUTANE
  • (+)1-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-BUTANE
  • 1-ISOTHISCYANATO-4-(METHYLSULFINYL)-BUTANE
  • 4-METHYLSULFINYLBUTYL ISOTHIOCYANATE
  • (-)-(4R)-SULFORAPHANE
  • D-SULFORAPHANE
  • DL-SULPHORAPHANE
  • (-)-ISOTHIOCYANATO-(4R)-(METHYLSULFINYL)BUTANE
  • L-SULFORAPHANE
  • Broccoli seed extract
  • sulphorane
  • Butane, 1-isothiocyanato-4-[(R)-methylsulfinyl]-
  • Anazolenum natricum
  • NSC 47734
  • NSC47734
  • NSC-47734
  • 142825-10-3
  • Chemopreventive Agents
  • Cancer Research
  • BioChemical
  • Phase II Enzyme Inducers
  • Aliphatics
  • Chiral Reagents
  • Inhibitors
  • Sulfur & Selenium Compounds