L-Sulforaphane

ChemicalBook > CAS DataBase List > L-Sulforaphane

Product Name: L-Sulforaphane
CAS No.: 142825-10-3
Chemical Name: L-Sulforaphane
Synonyms: NSC47734;NSC 47734;NSC-47734;sulphorane;L-Sulforafan;L-SULFORAPHAN;S-SULFORAPHANE;R-SULFORAPHANE;D-SULFORAPHANE;L-SULFORAPHANE
CBNumber: CB6765543
Molecular Formula: C6H11NOS2
Formula Weight: 177.29
MOL File: 142825-10-3.mol

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L-Sulforaphane Property

Boiling point:: 368.2±25.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: 40 mg/mL, soluble
form: liquid
color: slightly yellow
InChIKey: SUVMJBTUFCVSAD-UHFFFAOYSA-N

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Safety

Safety Statements: 23-24/25-22
WGK Germany: 3
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S6317
Product name: L-Sulforaphane
Purity: ≥95% (HPLC), oil
Packaging: 5mg
Price: $279
Updated: 2024/03/01

Cayman Chemical

Product number: 14797
Product name: L-Sulforaphane
Purity: ≥98%
Packaging: 1mg
Price: $45
Updated: 2024/03/01

Cayman Chemical

Product number: 14797
Product name: L-Sulforaphane
Purity: ≥98%
Packaging: 5mg
Price: $111
Updated: 2024/03/01

Cayman Chemical

Product number: 14797
Product name: L-Sulforaphane
Purity: ≥98%
Packaging: 10mg
Price: $177
Updated: 2024/03/01

Cayman Chemical

Product number: 14797
Product name: L-Sulforaphane
Purity: ≥98%
Packaging: 50mg
Price: $698
Updated: 2024/03/01

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L-Sulforaphane Chemical Properties,Usage,Production

Description

Sulforaphane is a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale.

Chemical Properties

L-Sulforaphane is a clear Pale Yellow Oil and It is an isothiocyanate derived from the natural compound glucoraphanin, which is abundant in cruciferous vegetables, including broccoli. soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

L-sulforaphane is an Antitumor agent and has antioxidant, anti-cancer, anti-ultraviolet, help clear lung bacteria, and prevent gout. It was found to inhibit chemically induced mammary tumor formation in rats. L-Sulforaphane has been reported to prevent NFκB binding, which results in downregulation of apoptosis inhibitors therefore inducing apoptosis. It also displays a capacity to inhibit intracellular, extracellular, and antibiotic-resistant strains of Helicobacter pylori. Additionally, L-Sulforaphane has been found to prevent clonogenicity. This Sulforaphane is sold in the L-enantiomer form.

Application

L-Sulforaphane was used to study Nrf2-mediated signaling in mouse primary preadipocytes and murine macrophage RAW 264.7 cell line.

Definition

ChEBI: (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.

Biochem/physiol Actions

L-Sulforaphane is a potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.
Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables. It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.

L-Sulforaphane Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Sulforaphane Suppliers

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View Lastest Price from L-Sulforaphane manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Sulforaphane 142825-10-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 1%-10% 98%
Supply Ability: 1000 kg
Release date: 2024-04-20

Hebei Zhanyao Biotechnology Co. Ltd

Product: Sulforaphane 142825-10-3
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-10-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: (R)-sulforaphane 142825-10-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

142825-10-3, L-SulforaphaneRelated Search:

Hydrogen Sulfide menisdaurin 4-Methoxybenzoic acid 2-(4-hydroxyphenyl)ethyl ester ALPHA-CARYOPHYLLENE Camphene GLUCOTROPAEOLIN Z-LIGUSTILIDE Muscone Hydroxycitric acid Xanthiside GLUCORAPHANIN Xanthiazone DL-Sulforaphane L-Sulforaphane ERYSOLIN ERUCIN 3-ISOTHIOCYANATOMETHYL-TETRAHYDRO-THIOPHENE 1,1-DIOXIDE DL-SULFORAPHANE--N/H DRY ICE

(R)-1-ISOTHIOCYANATO-4-(METHYLSULFINYL)BUTANE

R,S-SULFORAPHANE

R-SULFORAPHANE

S-SULFORAPHANE

SULFORAPHANE, L-

SULFORAPHANE, D-

SULFORAPHANE, DL-

4-METHYLSULPHINYLBUTYLISOTHIOCYANATE

L-SULFORAPHAN

(R)-1-Isothiocyanato-4-(methylsulfinyl)butane, 4-Methylsulfinylbutyl isothiocyanate

R-Sulforaphane (in ethanol)

(+)-1-ISOTHIOCYANATE-4R(METHYLSULFINYL)-BUTANE

1-ISOTHIOCYANATO-4-(METHYLSULFIYL)-BUTANE

((-)1-ISOTHIOCYANATO-4R-METHYLSULFINYL)BUTANE

(-)1-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-BUTANE

(+)1-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-BUTANE

1-ISOTHISCYANATO-4-(METHYLSULFINYL)-BUTANE

4-METHYLSULFINYLBUTYL ISOTHIOCYANATE

(-)-(4R)-SULFORAPHANE

D-SULFORAPHANE

DL-SULPHORAPHANE

(-)-ISOTHIOCYANATO-(4R)-(METHYLSULFINYL)BUTANE

L-SULFORAPHANE

Broccoli seed extract

sulphorane

Butane, 1-isothiocyanato-4-[(R)-methylsulfinyl]-

Anazolenum natricum

NSC 47734

NSC47734

NSC-47734

L-Sulforafan

Brassica oleracea L.var.italic Planch.

142825-10-3

Chemopreventive Agents

Cancer Research

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Sulfur & Selenium Compounds