ChemicalBook > CAS DataBase List > (RS)-MCPG

(RS)-MCPG

Product Name: (RS)-MCPG
CAS No.: 146669-29-6
Chemical Name: (RS)-MCPG
Synonyms: (RS)-MCPG;(+/-)MCPG;[+/-]-MCPG;alpha-MCPG;(RS)-MCPG, 10 mM in DMSO;alpha-Amino-4-Carboxy-alpha;(RS)-α-Methyl-4-carboxyphenylglycine;(RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE;(RS)-α-Methyl-4- carboxyphenylglycine;(±)-α-Methyl-(4-carboxyphenyl)glycine
CBNumber: CB6778633
Molecular Formula: C10H11NO4
Formula Weight: 209.2
MOL File: 146669-29-6.mol

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(RS)-MCPG Property

Boiling point:: 425.3±40.0 °C(Predicted)
Density: 1.390±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO : 6 mg/mL (28.68 mM; Need ultrasonic and warming)
form: Powder
pka: 1.76±0.10(Predicted)
color: White
CAS DataBase Reference: 146669-29-6(CAS DataBase Reference)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M4796
Product name: (±)-α-Methyl-(4-carboxyphenyl)glycine
Packaging: 25mg
Price: $546
Updated: 2024/03/01

Sigma-Aldrich

Product number: M4796
Product name: (±)-α-Methyl-(4-carboxyphenyl)glycine
Packaging: 5mg
Price: $190
Updated: 2023/06/20

Tocris

Product number: 0336
Product name: (RS)-MCPG
Purity: ≥99%(HPLC)
Packaging: 10
Price: $159
Updated: 2021/12/16

Tocris

Product number: 0336
Product name: (RS)-MCPG
Purity: ≥99%(HPLC)
Packaging: 50
Price: $658
Updated: 2021/12/16

TRC

Product number: M264743
Product name: (RS)-MCPG
Packaging: 5mg
Price: $115
Updated: 2021/12/16

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(RS)-MCPG Chemical Properties,Usage,Production

Uses

(RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist.

Biological Activity

Non-selective group I/group II metabotropic glutamate receptor antagonist. See (S)-isomer ((S)-a-Methyl-4-carboxyphenylglycine ).

in vivo

(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons^[1].
Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent^[2].

IC 50

mGluR

storage

Room temperature

(RS)-MCPG Preparation Products And Raw materials

Raw materials

Preparation Products

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(RS)-MCPG Suppliers

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146669-29-6, (RS)-MCPGRelated Search:

(RS)-A-METHYL-2-CARBOXYPH ENYLGLYCINE (RS-MCPG) E4CPG (2R)-2-AMINO-2-[4-(METHOXYCARBONYL)PHENYL]PROPANOIC ACID 4-((1R)-1-AMINO-1-CARBOXYETHYL)BENZOIC ACID (1R)-1-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE-1,6-DICARBOXYLIC ACID (1S)-1-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE-1,6-DICARBOXYLIC ACID AIDA (2S)-2-AMINO-2-[4-(ETHOXYCARBONYL)PHENYL]PROPANOIC ACID (2S)-2-AMINO-2-[4-(METHOXYCARBONYL)PHENYL]PROPANOIC ACID (2R)-2-AMINO-2-[4-(ETHOXYCARBONYL)PHENYL]PROPANOIC ACID (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE (RS)-MCPG

(+/-)MCPG

(+/-)-ALPHA-METHYL-(4-CARBOXYPHENYL)GLYCINE

(RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE

(RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE

(RS)-MCPG

(+/-)-A-METHYL-(4-CARBOXYPHENYL)GLYCINE

(+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE MET ABOTROPIC GLUTAMAT

[+/-]-MCPG

(R,S)-alpha-Methyl-4-carboxyphenylglycine(R,S)-MCPG

(RS)-α-Methyl-4-carboxyphenylglycine

4-[(1R)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate

4-[(1R)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate

4-[(1R)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate

alpha-Amino-4-Carboxy-alpha

alpha-Amino-4-Carboxy-alpha-Methyl-Benzeneacetic Acid

alpha-MCPG

Benzeneacetic acid, α-amino-4-carboxy-α-methyl-

(RS)-α-Methyl-4- carboxyphenylglycine

Metabotropic glutamate receptors,metabotropic,mGluR1,I/II,(RS) MCPG,mGluR5,(RS)-MCPG,group,inhibit,neurons,Inhibitor,mGluR3,(RS)MCPG,hippocampal,mGluR2,mGluR,glutamate,receptor

(R,S)-MCPG, Group I /II metabotropic glutamate antagonist

(RS)-MCPG, 10 mM in DMSO

(±)-α-Methyl-(4-carboxyphenyl)glycine

146669-29-6

Competitive antagonist at Group 1 (mGluR1 and mGluR5) and Group 2 (mGluR2 and mGluR3) metabotropic glutamate receptors.

Glutamate

Glutamate receptor