GITOXIGENIN

Product Name: GITOXIGENIN
CAS No.: 545-26-6
Chemical Name: GITOXIGENIN
Synonyms: GITOXIGENIN;Gitoxygenin;Gitoxigenin,98%;Digoxin Impurity 13;16β-hydroxydigitoxigenin;16BETA-HYDROXYDIGITOXIGENIN;5β,20(22)-Cardenolide-3β,14,16β-triol;3-beta,14,16-trioxycarden-(20:22)-olid;3-beta,14,16-trioxy-digen-(20:22)-olid;cardogenen-(20:22)-triol-(3-beta,14,16)
CBNumber: CB6780665
Molecular Formula: C23H34O5
Formula Weight: 390.51
MOL File: 545-26-6.mol

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GITOXIGENIN Property

Melting point:: ~230 °C
Boiling point:: 435.71°C (rough estimate)
Density: 1.0639 (rough estimate)
refractive index: 1.6120 (estimate)
storage temp.: −20°C
pka: 14.56±0.70(Predicted)
Merck: 13,4445

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Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 36/37/39-45
RIDADR: UN 1544 6.1/PG 1
WGK Germany: 3
RTECS: FH5391000
F: 10
HazardClass: 6.1(b)
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: G388725
Product name: Gitoxigenin
Packaging: 5mg
Price: $1890
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0000396
Product name: GITOXIGENIN
Purity: 95.00%
Packaging: 10MG
Price: $582.97
Updated: 2021/12/16

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GITOXIGENIN Chemical Properties,Usage,Production

Chemical Properties

light yellow flakes

Uses

Gitoxigenin is a related compound of Digitoxigenin, which has been used in a study to assess its stereochemical effects in cancer cytotoxicity. Digitoxigenin has also been used in a study to investigate the advantage of gold(I)-catalyzed glycosidation of glycosyl o-alkyl benzoates to assemble digitoxin.

Definition

ChEBI: Gitoxigenin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid and a 16beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide.

Biochem/physiol Actions

Structure-activity relationships for 16β-substituted digitoxigenins as inhibitors of Na+/K+ ATPases.

Purification Methods

Recrystallisation of gitoxigenin from aqueous EtOH produces plates of the sesquihydrate which dehydrate on drying at 100o in vacuo. It also recrystallises from Me2CO/MeOH and from EtOAc (the crystals contain 1 mol of EtOAc) with [] D +24.8o (c 1, dioxane). It has UV with max at 310, 485 and 520nm in 96% H2SO4. On heating with ethanolic HCl it yields digitaligenin with loss of H2O. [Smith J Chem Soc 23 1931, Beilstein 8 IV 2456.]

GITOXIGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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GITOXIGENIN Suppliers

Belgium 1 China 9 Germany 1 India 1 Japan 1 Slovakia 1 Switzerland 2 The Netherlands 1 United Kingdom 3 United States 9 Global 29

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 8888
Advantage: 60

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 0755-22202135 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 8814
Advantage: 58

Hangzhou Synstar pharmaceutical Technology CO.,Ltd

Tel: 0571-85361029
Fax: 0571-85361029
Email: synstar518@163.com
Country: China
ProdList: 1990
Advantage: 58

Hubei Xinyang Medical Technology Co., Ltd

Tel: 15347293736 15347293736
Fax: QQ：2853117752
Email: 2853117764@qq.com
Country: China
ProdList: 8327
Advantage: 58

QUALITY CONTROL SOLUTIONS LTD.

Tel: 0755-66853366; 13670046396
Email: ORDERS@QCSRM.COM
Country: China
ProdList: 18882
Advantage: 58

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

Tel: 15229059051
Email: 1027@dideu.com
Country: China
ProdList: 9982
Advantage: 58

China National Standard Pharmaceutical Corporation Limited

Tel: +8615391658522
Email: overseasales@yongstandards.com
Country: China
ProdList: 11922
Advantage: 58

545-26-6, GITOXIGENINRelated Search:

GITOXIGENIN gitoxigenin-glucodigitalosi gitoformate lanatoside D LANATOSIDE B gitoxigenin-tridigitoxosi Gitoxigenin 3-O-monodigitaloside 3-epi-Gitoxigenin GITOXIGENIN(RG) 3-epi-17βH-Gitoxigenin gitoxigenin bisdigitoxoside GITOXIGENIN 3-ACETATE OLEANDRIN, [3H]- 3beta,14,16beta-trihydroxy-5beta-card-20(22)-enolide 16-formate 16-Formyldigitalinum verum 16-ACETYLGITOXIN STROSPEOSIDE 20(22),5BETA-CARDENOLID-3BETA,14BETA,16BETA-TRIOL 3,16-DIACETATE

16β-Hydroxydigitoxigenin, 3β,14,16β-Trihydroxy-5β,20(22)-cardenolide, 5β,20(22)-Cardenolide-3β,14,16β-triol, 3β,14,16β,21-Tetrahydroxy-20(22)-norcholenic acid lactone

3β,14,16β-Trihydroxy-5β,14β-card-20(22)-enolide

Gitoxigenin,98%

3β,14,16β,21-Tetrahydroxy-20(22)-norcholenic acid lactone

3β,14,16β-Trihydroxy-5β,20(22)-cardenolide

5β,20(22)-Cardenolide-3β,14,16β-triol

3,14,16-trihydroxy-,(3-beta,5-beta,16-beta)-card-20(22)-enolid

3-beta,14,16-beta-trihydroxy-5-beta-card-20(22)-enolid

16β-hydroxydigitoxigenin

GITOXIGENIN

3-beta,14,16-trioxycarden-(20:22)-olid

3-beta,14,16-trioxy-digen-(20:22)-olid

cardogenen-(20:22)-triol-(3-beta,14,16)

delta(20,22)-2,14,16,21-tetrahydroxynorcholenicacidlactone

5BETA,20[22]-CARDENOLIDE-3BETA,14,16BETA-TRIOL

3BETA,14,16BETA,21-TETRAHYDROXY-20(22)-NORCHOLENIC ACID LACTONE

3BETA,14,16BETA-TRIHYDROXY-5BETA,20[22]-CARDENOLIDE

20(22),5BETA-CARDENOLID-3BETA, 14BETA, 16BETA-TRIOL

16BETA-HYDROXYDIGITOXIGENIN

3-beta,14,16-beta-trihydroxy-5-beta,14-beta-card-20(22)-enolide

Gitoxygenin

Card-20(22)-enolide, 3,14,16-trihydroxy-, (3β,5β,16β)-

Digoxin Impurity 13

545-26-6

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