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Frunevetmab

Product Name
Frunevetmab
CAS No.
1708936-80-4
Chemical Name
Frunevetmab
Synonyms
Frunevetmab;Research Grade Frunevetmab
CBNumber
CB68081023
Formula Weight
0
MOL File
Mol file
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Frunevetmab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Frunevetmab Chemical Properties,Usage,Production

Uses

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2].

in vivo

Frunevetmab (1.0-2.8 mg/kg; s.c; on days 0, 28, and 56) shows positive treatment effects in cats with naturally-occurring OA pain and associated mobility impairment and disability[1].

Animal Model:Cats with naturally-occurring OA pain and associated mobility impairment and disability[1]
Dosage:1.0-2.8?mg/kg
Administration:s.c; 3 times at 28-day intervals; on days 0, 28, and 56
Result:Reliefed the pain from osteoarthritis in cats.

References

[1] Margaret E Gruen, et al. Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats. J Vet Intern Med. 2021 Nov;35(6):2752-2762. DOI:10.1111/jvim.16291
[2] D P Gearing, et al. In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti-Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats. J Vet Intern Med. 2016 Jul;30(4):1129-37. DOI:10.1111/jvim.13985

Frunevetmab Preparation Products And Raw materials

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Preparation Products

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Frunevetmab Suppliers

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1708936-80-4, FrunevetmabRelated Search:


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