Crisaborole intermediate

Product Name: Crisaborole intermediate
CAS No.: 1187188-60-8
Chemical Name: Crisaborole intermediate
Synonyms: Crisaborole Impurity 28;Crisaborole Impurity 37;Crisaborole Impurity 59;5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol;5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol;Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
CBNumber: CB68131269
Molecular Formula: C14H13BO4
Formula Weight: 256.06
MOL File: 1187188-60-8.mol

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Crisaborole intermediate Property

Boiling point:: 432.1±55.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
pka: 7.05±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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Crisaborole intermediate Chemical Properties,Usage,Production

Uses

5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.

Crisaborole intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Crisaborole intermediate Suppliers

China 22 India 2 Global 24

Beijing Comparison Pharmaceutical Technology Co., Ltd

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ANHUI WITOP BIOTECH CO., LTD

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Yangzhou Changhua Biotechnology Co., Ltd.

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Shenzhen ruikai de biotechnology co., ltd.

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Changzhou Xianglong Pharmaceutical Technology Co., LTD

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View Lastest Price from Crisaborole intermediate manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Crisaborole Impurity 28 1187188-60-8
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-08

1187188-60-8, Crisaborole intermediateRelated Search:

5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol

Crisaborole Impurity 59

5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol

Crisaborole Impurity 37

Crisaborole Impurity 28

Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-

1187188-60-8